Characterizetion of Bioactive Compound of Sembung (Blumea balsamifera (L) Dc) Leaf Extract from Different Solvents

Abstract

Sembung (Blumea balsamifera (L) DC) is a species plant on Blumea genus, andAstereceae (compositae)
family. The leaf of Sembung is used by human as empiric treatment with extraction or infuse technique
to become “jamu” , its has function as functional drink, because its consist of flavonoid and alkaloid
compound, that has an antioxidant potency. The purpose of this research are to study of effect growth
leaf level and some of organic solvent to characterizetion simplisia powder extract Sembung leaf. The
methode of extraction by maseration, then analyze is done such as flavonoid, phenolic total, antioxidant
capacity, vitamin C, IC50, and determine volatil compound on the best treatment by GC-MS. The result
showed that very singnificant effect to all parameters analysis, and ethyl acetate extract on the tip of
Sembung leaf is the best treatment, that consist of flavonoid (204,58 mg QE/g db), phenolic total (225,33
mg GAE/ g db), vitamin C (451,92 mg/g db), antioxidant capacity (501,97 mg GAEAC/g db), and IC
50%(37,09 ppm). The GC-MS analysis showed there are benzena compound, monoterpene (camphor,
L-berneol), sesquiterpene (?-guaiene, caryophyllene, humulene) and diterpene (neophytadiene) on the
best treatment.