Review: Comparison of Conventional and Modern Compounding in the Preparation of Turmeric (Curcuma domestica Val.) Based Pharmaceutical Preparations
Abstract
Conventional compounding practices in traditional medicine have been established for many years; however, they often encounter challenges in ensuring product quality, consistency, and safety. This study aims to compare conventional and modern compounding methods in the preparation of pharmaceutical products derived from turmeric rhizomes (Curcuma domestica Val). The research employs a literature review, drawing from a selection of studies related to the formulation of these pharmaceutical products from accredited scientific databases. The obtained data were analyzed descriptively to evaluate the comparison between the two methods in terms of effectiveness, stability, safety, and cost. The findings reveal that both methods possess distinct advantages and disadvantages, offering valuable insights into key aspects of producing pharmaceutical preparations from turmeric rhizomes. Ultimately, this research enhances the understanding of each method's implications in pharmaceutical production, particularly within the realm of traditional medicine.
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References
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Sidoretno, W. M., Rosaini, H., Makmur, I., & Kharisma, F. D. (2022). Formulation and Evalution of Effervescent Granules Combination Extract Red Ginger, Curcuma and Cinnamon. Journal Of Pharmacy and Science, 5(1), 21-35.
Subagia, I. K., Januarta, I. G. A., Arisanti, C. I. S., & Samirana, P. O. (2019). Optimasi Konsentrasi Pulvis Gummi Arabicum (PGA) sebagai Emulgator Formulasi Emulsi Ekstrak Rimpang Kunyit (Curcuma longa). J. Farm. Udayana, 8(1), 22. https://doi.org/10.24843/JFU.2019.v08.i01.p04.
Suena, N.M.D.S., Suradnyana, I.G.M., dan Juanita, R.A. (2021). Formulasi dan Uji Aktivitas Antioksidan Granul Effervescent dari Kombinasi Ekstrak Kunyit Putih (Curcuma Zedoaria) dan Kunyit Kuning (Curcuma Longa L.). Jurnal Ilmiah Medicamento. 7(1):32-40.
Zamarioli, C. M., Martins, R. M., Carvalho, E. C., and Freitas, L. A. P. (2015). Nanoparticles containing curcuminoids (Curcuma longa): development of topical delivery formulation. Brazilian Journal of Pharmacognosy, 25, 53-60.
Akram, M.F.A., Arisanty., dan Ibrahim, I. (2022). Farmulasi Granul Effervescent Kunyit (Curcumae domestica) dan Asam Jawa (Tamarindus indica). AKFARINDO. 7(2): 66-70.
Altemimi, A., Lakhssassi, N., Baharlouei, A., Watson, D.F., and Lightfoot, D.A. (2017). Phytochemicals: Extraction, Isolation, and Identification of Bioactive Compounds from Plant Extracts. Plants. 6(42): 1-23
Arushi, K. S., Kumari, G., Saha, S., Mukherjee, R., & Kanika, A. S. (2024). Development And Evaluation Of Antibacterial Turmeric Ointment. YMER. 23(03): 1173-1184.
Bácskay, I., Sinka, D., Józsa, L., Vasas, G., Újhelyi, Z., Fehér, P., Szilvássy, Z. (2021). Formulation and investigation of turmeric extract and sodium benzoate loaded capsules. Acta Pharmaceutica Hungarica, 91(1), 11-20.
Chen, Y. C., & Chen, B. H. (2018). Preparation of Curcuminoid Microemulsions from Curcuma longa L. to Enhance Inhibition Effects on Growth of Colon Cancer Cells HT-29. RSC advances, 8(5), 2323-2337.
Dwiaini, I. (2019). Peranan Teknologi Informasi pada Bidang Farmasi. Jurnal SIMTIKA, 2(3), 32-34.
Elkhateeb, O., Badawy, M.E.I., Tohamy, H.G., Ahmed, H.A., El-Kammar, M., and Elkhendany, H. (2023). Curcumin-infused Nanostructured Lipid Carriers: A Promising Strategy for Enhancing Skin Regeneration and Combating Microbial Infection. BMC Veterinary Research. 19(206): 1-13.
Ermawati, D.E., Sulaiman, T.N.S., dan Purwantini, I. (2017). Optimasi Formula Tablet Hisap Ekstrak Kunyit (Curcuma longa L.) Menggunakan Campuran Bahan Pengisi Manitol-Laktosa dengan Metode Simplex Lattice Design. Journal of Pharmaceutical Science and Clinical Research, 02, 53-65.
Estefania, K. V., Silalahi, J., Sumaiyah., and Satria, D. (2022). Formulation and Evaluation of Cream Turmeric Extract Preparations from Turmeric Rhizomes (Curcuma domestica Val.). Indonesian Journal of Pharmaceutical and Clinical Research, 5(1), 1-9.
Goncalves, G. M. S., Silva, G. H. D., Barros, P. P., Srebernich, S. M., Shiraishi, C. T. C., Camargos, V. R. D., et al. (2014). Use of Curcuma longa in cosmetics: extraction of curcuminoid pigments, development of formulations, and in vitro skin permeation studies. Brazilian Journal of Pharmaceutical Science, 50(4), 885-893.
Handayani., Sofaria, R., dan Puspitasari, R.N. (2021). The Effects of Turmeric Infusion and Turmeric Juice (Curcuma domestica) on The Staphylococcus aureus Growth in Vitro. International Islamic Medical Journal. 2(2): 54-60.
Hernawan, J. Y., Christiandari, H., & Putri, F. (2024). Formulasi Sediaan Kapsul Penambah Nafsu Makan Ekstrak Kunyit (Curcuma domestica). Jurnal Permata Indonesia, 15(1), 37-42.
Husnudin, U. B. & Elhany, N. A. (2022). Pelatihan Pembuatan Jahe Dan Temulawak Instan Di Kalangan Ibu Rumah Tangga Desa Talkandang Kecamatan Situbondo. Jurnal Pengabdian Masyarakat Bumi Rafflesia, 5(2), 886-889.
Indriaty, S., Firmansyah, D., Rani, D. A., dan Rodiah, D. (2020). Formulasi dan Uji Iritasi Krim Ekstrak Etanol Rimpang Kunyit (Curcuma longa Linn.). Medical Sains, 5(1), 51-62.
Larasati, D., Istiqomah, F., & Hernowo, B. (2022). Evaluasi sifat fisik salep kunyit (Curcuma domestica) dengan variasi konsentrasi vaselin album. Jurnal Kesehatan Madani Medika (JKMM), 13(1).
Megananda, R. C., Primiani, C. N., and Anindhita, M. N. (2024). Qualitative Analysis of Phytochemical Compounds in Turmeric Powder as Functional Drink. Biodidaktika: Jurnal Biologi dan Pembelajarannya, 19(1), 7-16.
Naywa, P., Harahap, N., Maitrianti, C., dan Sakdiah H. (2024). Analisis Potensi Minuman Herbal dari Kunyit (Curcuma longa) dan Asam Jawa (Tamarindus indica). Jurnal Ilmiah Mahasiswa, 2(1), 20-28.
Novita, R., Purwani, S.P.M.E., dan Jayantiari, I.G.A.M.R. (2023). Analisis Hukum Peredaran Obat Tradisional: Menjaga Keamanan dan Keberlanjutan dalam Masyarakat. Jurnal Interpretasi Hukum, 4(3), 595-607.
Pratama, R., Saputro, M.R., Sani, A.R., Awaliyah, R.S.R. (2024). Pengaruh Eksipien Terhadap Sifat Fisik Granul Effervescent : Review. 2(1):137-154.
Sasmita, I. R. A., Apriliyanti, M.W., Suryanegara, M.A., Ana, F.W.R. (2021). Pengaruh Penambahan Manitol dan Amilum Manihot terhadap Sifat Fisik dan Sensoris Tablet Hisap Kunyit Asam. Jurnal Ilmiah Inovasi, 21(3), 183-189.
Shah, N. M., Kassim, A. S. M., & Razak, A. H. A. (2022). Production of Curcumin-loaded Nanoemulsion from Curcuma longa (Turmeric) Extract and Its Antimicrobial Activity. Progress in Engineering Application and Technology, 3(2), 058-069.https://doi.org/10.30880/peat.2022.03.02.006
Shah, R. S. (2021). Formulation and evaluation of Turmeric emulgel. Asian Journal of Pharmacy and Technology, 11(3), 213-219.
Sidoretno, W. M., Rosaini, H., Makmur, I., & Kharisma, F. D. (2022). Formulation and Evalution of Effervescent Granules Combination Extract Red Ginger, Curcuma and Cinnamon. Journal Of Pharmacy and Science, 5(1), 21-35.
Subagia, I. K., Januarta, I. G. A., Arisanti, C. I. S., & Samirana, P. O. (2019). Optimasi Konsentrasi Pulvis Gummi Arabicum (PGA) sebagai Emulgator Formulasi Emulsi Ekstrak Rimpang Kunyit (Curcuma longa). J. Farm. Udayana, 8(1), 22. https://doi.org/10.24843/JFU.2019.v08.i01.p04.
Suena, N.M.D.S., Suradnyana, I.G.M., dan Juanita, R.A. (2021). Formulasi dan Uji Aktivitas Antioksidan Granul Effervescent dari Kombinasi Ekstrak Kunyit Putih (Curcuma Zedoaria) dan Kunyit Kuning (Curcuma Longa L.). Jurnal Ilmiah Medicamento. 7(1):32-40.
Zamarioli, C. M., Martins, R. M., Carvalho, E. C., and Freitas, L. A. P. (2015). Nanoparticles containing curcuminoids (Curcuma longa): development of topical delivery formulation. Brazilian Journal of Pharmacognosy, 25, 53-60.
Published
2025-01-10
How to Cite
DEWI, Kadek Ratna Sari et al.
Review: Comparison of Conventional and Modern Compounding in the Preparation of Turmeric (Curcuma domestica Val.) Based Pharmaceutical Preparations.
Jurnal Farmasi Udayana, [S.l.], p. 85-97, jan. 2025.
ISSN 2622-4607.
Available at: <https://ojs.unud.ac.id/index.php/jfu/article/view/120030>. Date accessed: 10 jan. 2025.
doi: https://doi.org/10.24843/JFU.2024.v13.i02.p07.
Section
Articles
