PEMANFAATAN TEH KOMBUCHA SEBAGAI OBAT HIPERURISEMIA MELALUI PENURUNAN KADAR 8-HIDROKSI-2-DEOKSIGUANOSIN

  • Made Baruna Jayadilaga
  • Ida Bagus Putra Manuaba
  • Ni Luh Rustini

Abstract

The utilization of kombucha tea as hyperuricemia medicine by decreasing levels of 8-hydroxy-2-deoksiguanosin (8-OHdG) has been carried out. This study aimed to determine the ability of kombucha tea to decrease uric acid and 8-OHdG levels in hyperuricemia rats. This research is true experimental with posttest only control group design. Rats that had experienced hyperuricemia were given kombucha tea dose of 10 mL/kg body weight and 40 mL/kg body weight of 4, 8, and 12 days fermentation period. The results showed that kombucha tea can decrease uric acid and 8-OHdG levels in hyperuricemia rats. The best dose of kombucha tea in decreasing uric acid and 8-OHdG levels was 40 mL/kg body weight with 8 days fermentation period. The decrease of uric acid and 8-OHdG levels were 93.88% and 85.89% respectively.

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Author Biographies

Made Baruna Jayadilaga
Jurusan Kimia FMIPA Universitas Udayana, Kampus Bukit Jimbaran
Ida Bagus Putra Manuaba
Jurusan Kimia FMIPA Universitas Udayana, Kampus Bukit Jimbaran
Ni Luh Rustini
Jurusan Kimia FMIPA Universitas Udayana, Kampus Bukit Jimbaran
Published
2014-01-01
How to Cite
JAYADILAGA, Made Baruna; MANUABA, Ida Bagus Putra; RUSTINI, Ni Luh. PEMANFAATAN TEH KOMBUCHA SEBAGAI OBAT HIPERURISEMIA MELALUI PENURUNAN KADAR 8-HIDROKSI-2-DEOKSIGUANOSIN. Jurnal Kimia (Journal of Chemistry), [S.l.], jan. 2014. ISSN 2599-2740. Available at: <https://ojs.unud.ac.id/index.php/jchem/article/view/9755>. Date accessed: 21 nov. 2024. doi: https://doi.org/10.24843/JCHEM.2014.v08.i01.p17.
Section
Articles

Keywords

Kombucha tea, uric acid, hyperuricemia, oxidative stress, 8-OHdG

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