ACTIVITY OF BAY LEAF EXTRACT (Eugenia polyantha) AS ANTI-INFLAMMATORY IN WHITE RAT (Rattus norvegicus)

NARRATIVE REVIEW

  • Ida Ayu Nadia Kusumastuti Udayana University
  • Made Krisna Adi Jaya Udayana University

Abstract

Background: Inflammation is the body's defense response against foreign body invasion, tissue injury, or both caused by microorganisms, mechanical trauma, chemical compounds, and physical factors. Anti-inflammatory agents can be used to treat inflammation. Bay leaves are one example of a plant that can be used. Ethanol extract and water extract of a bay leaf can be anti-inflammatory because they contain flavonoids.  Objectives: The purpose of this study was to see how effective ethanol extract and aqueous extract of bay leaf were as anti-inflammatory agents in mice. Methods: This study employs a systematic literature review approach, descriptive qualitative research, and library research. Results: The most efficacious dose was 150 mg/kg BW at a 70 percent concentration and at an 80 percent concentration for ethanol extract of bay leaves, and 50 mg/kg BW for the aqueous extract of bay leaves. Conclusion: Based on the results of this study, it can be concluded that bay leaf (Eugenia polyantha) ethanol extract and aqueous extract have anti-inflammatory activities


Keywords: Anti-inflammatory, Bay Leaf, Diclofenac sodium, Ethanol Extract, Aqueous

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Published
2022-06-05
How to Cite
KUSUMASTUTI, Ida Ayu Nadia; JAYA, Made Krisna Adi. ACTIVITY OF BAY LEAF EXTRACT (Eugenia polyantha) AS ANTI-INFLAMMATORY IN WHITE RAT (Rattus norvegicus). Journal Pharmaceutical Science and Application, [S.l.], v. 4, n. 1, p. 26-32, june 2022. ISSN 2301-7708. Available at: <https://ojs.unud.ac.id/index.php/jpsa/article/view/85577>. Date accessed: 17 nov. 2024. doi: https://doi.org/10.24843/JPSA.2022.v04.i01.p04.