THE EFFECTIVENESS TEST OF INFUSION CELERY ROOT (Apium graveolens L.) AS A DIURETIC IN WISTAR MALE WHITE RATS (Rattus Norvegicus)

A LITERATURE STUDY

  • Ida Ayu Dhea Rahnia Udayana University
  • Made Krisna Adi Jaya Udayana University
DOI: https://doi.org/10.24843/JPSA.2022.v04.i01.p03

Abstract

Background: Hypertension is defined by persistently elevated arterial blood pressure. The increase in systolic blood pressure is generally>140mmHg or diastolic blood pressure> 90mmHg. The prevalence of hypertension increases with lifestyle changes. Objective: To determine the diuretic effect of celery (Apium graveolens L.) on male wistar rats (Rattus norvegicus). Methods: This research uses a literature study method, the type of the research is descriptive qualitative with literature research (library research) systematic. Results: Based on research data, there were 5 groups of mice that received different treatments. Among the five treatment groups, 0.5 % CMC suspension (KP-) showed the least mean cumulative urine volume, and furosemide suspension (KP+) showed a large mean cumulative urine volume when compared to negative controls. Conclusion: Celery root infusion can increase urine volume because it contains flavonoids that play a role in increasing urine volume (diuresis).


Keywords: Diuretic, Celery (Apium graveolens L.), Furosemide, Hypertension, Wistar rats

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Published
2022-06-05
How to Cite
RAHNIA, Ida Ayu Dhea; JAYA, Made Krisna Adi. THE EFFECTIVENESS TEST OF INFUSION CELERY ROOT (Apium graveolens L.) AS A DIURETIC IN WISTAR MALE WHITE RATS (Rattus Norvegicus). Journal Pharmaceutical Science and Application, [S.l.], v. 4, n. 1, p. 19-25, june 2022. ISSN 2301-7708. Available at: <https://ojs.unud.ac.id/index.php/jpsa/article/view/85576>. Date accessed: 30 june 2024. doi: https://doi.org/10.24843/JPSA.2022.v04.i01.p03.
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Vol 4 No 1 (2022): Journal Pharmaceutical Science and Application
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Articles
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Creative Commons License

This work is licensed under a Creative Commons Attribution 4.0 International License.