SUPLEMEN EKSTRAK DAUN SIRIH, Piper betle, Lin DALAM MENURUNKAN KADAR MALONDIALDEHID PADA TIKUS WISTAR

  • I W. Suirta Program Studi Kimia FMIPA Universitas Udayana, Jimbaran, Bali, Indonesia
  • I. A. R. A. Asih Program Studi Kimia FMIPA Universitas Udayana, Jimbaran, Bali, Indonesia

Abstract

Betel leaf extract supplements, Piper betle Lin , was made by extracting maceration of betel leaves with ethanol 96%. Phytochemical screening of betle leaf extract obtained secondary metabolites such as : terpenoids, steroids, phenolics, and saponins . The results of the antioxidant activity test test showed that n-hexane fraction was more reactive as an antioxidant (IC50 26,73 mg/L)  than the diethyl ether fraction (IC50 114,54 mg/L). The MDA analysis showed that the betel leaves have a very good ability to reduce MDA levels. The concentration of MDA with addition of allopurinol (as positive control) was 0,41±0,0021?L/mL, while with addition of betel leaves the level was 0,44±0,0021?L/mL. The structure identification obtained active antioxidant compounds such as: cavicol, eugenol, caryophilene and isoeugenol.


Keywords : betel leaf, malondialdehyde, Piper betle, wistar rat

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Published
2019-07-31
How to Cite
SUIRTA, I W.; ASIH, I. A. R. A.. SUPLEMEN EKSTRAK DAUN SIRIH, Piper betle, Lin DALAM MENURUNKAN KADAR MALONDIALDEHID PADA TIKUS WISTAR. Jurnal Kimia (Journal of Chemistry), [S.l.], p. 185-190, july 2019. ISSN 2599-2740. Available at: <https://ojs.unud.ac.id/index.php/jchem/article/view/51716>. Date accessed: 21 nov. 2024. doi: https://doi.org/10.24843/JCHEM.2019.v13.i02.p10.
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Articles