PENGARUH FREKUENSI PEMBERIAN EKSTRAK TANGKAI JARAK CINA (JATROPHA MULTIFIDA) TERHADAP PENYEMBUHAN LUKA PADA MENCIT (MUS MUSCULUS)

Abstract

Wound  care  is  necessary  in  assisting  the  process  of  wound  healing.  Coral
bush contains chemical compounds such as flavonoids that act as anti-bacterial which
disrupt the integrity of bacterial cell membranes, coral bush also  contains alkaloids,
saponins  and  tannins  that  help  the  healing  process  of  wounds.  This  study  aimed  to
determine the effect of frequency giving stalk extract coral bush in wound healing in
mice.  This  type  of  research  True  Experiment  with  Post  Test  Only  Control  Group
Design. Group one (stalk extract coral bush once daily), group two (stalk extract coral
bush twice daily) and group three (NaCl 0.9%  as  control). Sampling technique with
Simple Random Sampling by 27 mice. Assessment is done every day in 10 days  by
measuring the decrease in mice  skin erythema in the analysis with Color Picker Tool
program. The group one average time is 8.11 days of wound healing. Two groups is
6.44 days. Three groups, namely 9.11 days. Krukal Wallis test results showed that the
value  Asymp.  Sig  was  0.000  (p  <0.05)  so  that  it  can  be  concluded  that  there  was
effect  of  the  frequency  giving  stalk  extract  coral  bush  on  wound  healing  in  mice.
Mann  Whitney  test  results  showed  that  the  extract  stalk  coral  bush  twice  a  day  is
better than once a day and NaCl 0.9% in mice. Based on these results suggested the
use of coral bush in wound healing.