THE ADDITION OF MORINGA FLOUR IN THE DIET INCREASED THE WEIGHT OF THE WHITE RAT LIVER
Abstract
This study aims to determine the addition of moringa flour (Moringa oleifera) in the feed to the weight of the liver of white rats (Rattus norvegicus). Moringa leaf flour was administered orally in 20 rats divided into 5 treatment groups with 0%, 2.5%, 5.0%, 10% and 20% concentration respectively with five replicates for one month. The white mouse was dissected and weighed heavily. This study used a Completely Randomized Design (RAL). The data obtained were analyzed using ANOVA (analysis of variance), and continued by Duncan Multiple Range Test. The results obtained were the addition of 20 ml of Moringa oleifera flour in the diet to increase the liver weight of white rat (Rattus norvegicus), while the addition of maize flour 10%, 5% and 2.5% did not affect to the white rat’s (Rattus norvegicus) liver weight.
Downloads
Download data is not yet available.
References
Agustiana D, Endang T, Sujuti H. 2011. Serbuk Daun Kelor Menurunkan Derajat Perlemakan Hati dan Ekspresi Interleukin-6 Hati Tikus dengan Kurang Energi Protein. J. Kedokteran Brawijaya. 26(3): 125-130.
Brzoska MM, Jakoniuk JM, Marcinkiewicz BP, Sawicki B. 2003. Liver and Kidney Function and Histology in Rats Exposed to Cadmium and Ethanol. Med. Council on Alcohol. 38(1): 2-10.
Cunningham GF, Gant NF, Leveno KJ. 2006. Gangguan Pertumbuhan Janin. Obstetri Williams Vol. 1 Ed 21. Jakarta; EGC. Pp. 825-850.
Dwi RP. 2015. Pengaruh Ekstrak Daun Kelor Terhadap Berat Badan dan Panjang Badan Anak Tikus Galur Wistar. J. Ilmiah Rekam Medis dan Informatika Kesehatan. (5): 15-22.
Ekwasita RP. 2009. Pasokan dan Permintaan Tanaman Obat Indonesia serta Arah Penelitian dan Pengembangannya. Perspektif. 8(1): 52-64.
Guyton AC, Hall JE. 2006. Textbook of Medical Physiology. 11th Ed. Elsevier Saunders. Philadelphia. USA.
Ibok OWOE, Deborah O. 2008. Nutritional potential of two leaty vegetables moringa oleifera and ipomoea batas leaves. Sci. Res. Essy. 3(2): 057-060.
Joni MS, Sitorus M, Kathrina N. 2008. Cegah Malnutrisi dengan Kelor. Kanisius. Yogyakarta.
Krisnadi AD. 2015. Kelor Super Nutrisi. Edisi Revisi Maret. Kelorina.com. Pusat Informasi dan Pengembangan Tanaman Kelor Indonesia. Lembaga Swadaya Masyarakat. Media Peduli Lingkungan.
Mahadewi SA, Purwani STD, Ariantari NP, Kardena IM. 2013. Pengaruh Pemberian Ekstrak Etanol Daun Spondias pinnata Terhadap Berat Organ Hati Mencit Betina. J. Farmasi Udayana. 2(3): 100-103.
Malarkey DE, Johnson K, Ryan L, Boorman G, Maronpot RR. 2005. New Insights into Functional Aspects of 133 Liver Morphology. Toxicol. Pathol. 33: 27-34.
Michael B, Yano B, Sellers RS, Perry R, Morton D, Roomie N, Johnson JK, Schafer K. 2007. Evaluation of Organ Weights for Rodent and Non-Rodent Toxicity Studies: A Review of Regulatory Guidelines and a Survey of Current Practises. Toxicol. Pathol. 35: 742-750.
Prihati DR. 2015. Pengaruh Ekstrak Daun Kelor Terhadap Berat Badan dan Panjang Badan Anak Tikus Galur Wistar. J. Ilmiah Rekam Medis dan Informatika Kesehatan. 5(2):15-22.
Sellers RS, Morton D, Michael B, Roome N, Johnson JK, Yano BR, Perry R, Schaffer K. 2007. Society of Toxicologic Pathology Position Paper: Ogan Weight Recommendation for Toxicology Studies. Toxicol. Pathol. 35: 751-755.
Tappi ES, Lintong P, Loho LL. 2013. Gambaran Histopatologi Hati Tikus Wistar yang diberikan Jus Tomat (Solanum Lycopersicum) Pasca Kerusakan Hati Wistar yang diinduksi Karbon Tetraklorida (CCl4). J. e-Biomedik. 1(3): 1126-1129.
Wiknjosastro GH. 2008. Pertumbuhan Janin Terhambat.Ilmu Kebidanan. Jakarta: Bina Pustaka. Pp. 696-717.
Winter AR, Funk EM. 1960. Poultry Science and Practice. 5thed. J. B. Lippincott Co. Chicago, Philadelphia, New York.
Zakaria, Thamrin A, Lestari RS, Hartono R. 2012. Penambahan Tepung Daun Kelor pada Menu Makanan Sehari-hari Dalam Upaya Penanggulangan Gizi Kurang Pada Anak Balita. Media Gizi Pangan. 13: 41-47.
Brzoska MM, Jakoniuk JM, Marcinkiewicz BP, Sawicki B. 2003. Liver and Kidney Function and Histology in Rats Exposed to Cadmium and Ethanol. Med. Council on Alcohol. 38(1): 2-10.
Cunningham GF, Gant NF, Leveno KJ. 2006. Gangguan Pertumbuhan Janin. Obstetri Williams Vol. 1 Ed 21. Jakarta; EGC. Pp. 825-850.
Dwi RP. 2015. Pengaruh Ekstrak Daun Kelor Terhadap Berat Badan dan Panjang Badan Anak Tikus Galur Wistar. J. Ilmiah Rekam Medis dan Informatika Kesehatan. (5): 15-22.
Ekwasita RP. 2009. Pasokan dan Permintaan Tanaman Obat Indonesia serta Arah Penelitian dan Pengembangannya. Perspektif. 8(1): 52-64.
Guyton AC, Hall JE. 2006. Textbook of Medical Physiology. 11th Ed. Elsevier Saunders. Philadelphia. USA.
Ibok OWOE, Deborah O. 2008. Nutritional potential of two leaty vegetables moringa oleifera and ipomoea batas leaves. Sci. Res. Essy. 3(2): 057-060.
Joni MS, Sitorus M, Kathrina N. 2008. Cegah Malnutrisi dengan Kelor. Kanisius. Yogyakarta.
Krisnadi AD. 2015. Kelor Super Nutrisi. Edisi Revisi Maret. Kelorina.com. Pusat Informasi dan Pengembangan Tanaman Kelor Indonesia. Lembaga Swadaya Masyarakat. Media Peduli Lingkungan.
Mahadewi SA, Purwani STD, Ariantari NP, Kardena IM. 2013. Pengaruh Pemberian Ekstrak Etanol Daun Spondias pinnata Terhadap Berat Organ Hati Mencit Betina. J. Farmasi Udayana. 2(3): 100-103.
Malarkey DE, Johnson K, Ryan L, Boorman G, Maronpot RR. 2005. New Insights into Functional Aspects of 133 Liver Morphology. Toxicol. Pathol. 33: 27-34.
Michael B, Yano B, Sellers RS, Perry R, Morton D, Roomie N, Johnson JK, Schafer K. 2007. Evaluation of Organ Weights for Rodent and Non-Rodent Toxicity Studies: A Review of Regulatory Guidelines and a Survey of Current Practises. Toxicol. Pathol. 35: 742-750.
Prihati DR. 2015. Pengaruh Ekstrak Daun Kelor Terhadap Berat Badan dan Panjang Badan Anak Tikus Galur Wistar. J. Ilmiah Rekam Medis dan Informatika Kesehatan. 5(2):15-22.
Sellers RS, Morton D, Michael B, Roome N, Johnson JK, Yano BR, Perry R, Schaffer K. 2007. Society of Toxicologic Pathology Position Paper: Ogan Weight Recommendation for Toxicology Studies. Toxicol. Pathol. 35: 751-755.
Tappi ES, Lintong P, Loho LL. 2013. Gambaran Histopatologi Hati Tikus Wistar yang diberikan Jus Tomat (Solanum Lycopersicum) Pasca Kerusakan Hati Wistar yang diinduksi Karbon Tetraklorida (CCl4). J. e-Biomedik. 1(3): 1126-1129.
Wiknjosastro GH. 2008. Pertumbuhan Janin Terhambat.Ilmu Kebidanan. Jakarta: Bina Pustaka. Pp. 696-717.
Winter AR, Funk EM. 1960. Poultry Science and Practice. 5thed. J. B. Lippincott Co. Chicago, Philadelphia, New York.
Zakaria, Thamrin A, Lestari RS, Hartono R. 2012. Penambahan Tepung Daun Kelor pada Menu Makanan Sehari-hari Dalam Upaya Penanggulangan Gizi Kurang Pada Anak Balita. Media Gizi Pangan. 13: 41-47.
Published
2018-08-27
How to Cite
BOTHA, Maria Natalia Dhiu; SETIASIH, Ni Luh Eka; SUSARI, Ni Nyoman Werdi.
THE ADDITION OF MORINGA FLOUR IN THE DIET INCREASED THE WEIGHT OF THE WHITE RAT LIVER.
Buletin Veteriner Udayana, [S.l.], p. 132-136, aug. 2018.
ISSN 2477-2712.
Available at: <https://ojs.unud.ac.id/index.php/buletinvet/article/view/33720>. Date accessed: 25 apr. 2024.
doi: https://doi.org/10.24843/bulvet.2018.v10.i02.p05.
Section
Articles
