Aktivitas Anti Luka Bakar dari Gel Minyak Kemiri (Aleurites moluccana L.) terhadap Tikus Putih (Rattus novergicus)
Abstract
Candlenut oil is often used as a traditional medicine that is used topically, generally used to treat hair and treat burns. The purpose of this study was to test the anti-burn activity of candlenut oil which has been formulated in the form of a gel. The method used was a laboratory experimental where candlenut oil was formulated in gel containing various concentrations of active substances 15, 20 and 25%, then tested for burn wound healing activity in mice induced by hot plates. Observation of wound healing time was carried out for 21 days. The results showed that 25% candlenut oil gel were similar to the positive control Burnazin® in healing burn wound. All of the candlenut oil gel formulas were completely fulfilled the requirement for gel preparation and have activity to heal burn wound.
Keywords: Aleurites moluccana, burn wound healing activity, gel
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References
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Nokhala, A., & Siddiqui, M. J. (2020). Phytochemicals and biological activity of Tetracera scandens Linn. Merr. (Dilleniaceae): A short review. Journal of Pharmacy & Bioallied Sciences, 22(3), 217–222.
Oktiarni, D., Manaf, S., & Suripno. (2012). Pengujian Ekstrak Daun Jambu Biji (Psidium guajava Linn.) Terhadap Penyembuhan Luka Bakar Pada Mencit (Mus musculus). Gradien, 8(1), 752–755.
Prabowo, W. C. (2020). Antibacterial Activity of Scopoletin from Stem Bark of Aleurites moluccana Against Salmonella typhi. Journal of Tropical Pharmacy and Chemistry, 5(1), 29–32.
Sulistyo, H., Rahayu, S. S., Winoto, G., & Suardjaja, I. M. (2008). Biodiesel Production from High Iodine Number Candlenut Oil. World Academy of Science, 48, 485–488.
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Yamlean, P. V., Queljoe, E. De, & Bodhi, W. (2019). Base Variations of the Candlenut Oil Ointment (Aleurites moluccana) and the Healing Potential Test on Wounds in Rabbits. Jurnal Ilmu Kefarmasian Indonesia, 17(2), 232–237.
Ganesan, K., & Xu, B. (2017). A critical review on polyphenols and health benefits of black soybeans. Nutrients, 9(5), 1–17. https://doi.org/10.3390/nu9050455
Kozier, B. (1995). Fundamental of Nursing, Conceps, Process and Practice (4th ed.). Adison Wesley.
Krishnaveni, M. R. D. (2014). Qualitative and Quantitative Study of Phytochemicals in Muntingia calabura L. Leaf and Fruit. World Journal of Pharmaceutical Research, 3(6), 1687–1696.
Krisnawati, H., & Kallio, M. (2011). Aleurites moluccana (L.) Willd. Ecology, silviculture and productivity. Center for International Forestry Research (CIFOR).
Lestari, M. S., Himawan, T., Abadi, A. L., & Retnowati, R. (2015). Research Article Toxicity and phytochemistry test of methanol extract of several plants from papua using Brine Shrimp Lethality Test ( BSLT ). Journal of Chemical and Pharmaceutical Research, 7(4), 866–872.
Martin, C., Moure, A., Martin, G., Carrillo, E., Dominguez, H., & Parajo, J. C. (2010). Fractional Characterisation of Jatropha, Neem, Moringa, Trisperma, Castor and Candlenut Seeds as Potential Feedstocks for biodiesel production in Cuba. Biomass and Bioenergy, 34(4), 533–538.
Meyre-Silva, C., Mora, T. C., Biavatti, M. W., Santos, A. R. S., Dal-Magro, J., Yunes, R. A., & Cechinel-Filho, V. (1998). Preliminary Phytochemical and Pharmacological Studies of Aleurites moluccana Leaves [L.] Willd. Phytomedicine, 5(2), 109–113.
Murti, D. A. (2017). Efektifitas Salep Getah Jarak Pagar (Jatropha curcas L) Pada Fase Epitelisasi Penyembuhan Luka Sayat Kulit Mencit (Mus musculus) Dengan Pewarnaan Masson Trichrome. Jurnal Ilmiah Mahasiswa Veteriner, 1(3), 465–472.
Nokhala, A., & Siddiqui, M. J. (2020). Phytochemicals and biological activity of Tetracera scandens Linn. Merr. (Dilleniaceae): A short review. Journal of Pharmacy & Bioallied Sciences, 22(3), 217–222.
Oktiarni, D., Manaf, S., & Suripno. (2012). Pengujian Ekstrak Daun Jambu Biji (Psidium guajava Linn.) Terhadap Penyembuhan Luka Bakar Pada Mencit (Mus musculus). Gradien, 8(1), 752–755.
Prabowo, W. C. (2020). Antibacterial Activity of Scopoletin from Stem Bark of Aleurites moluccana Against Salmonella typhi. Journal of Tropical Pharmacy and Chemistry, 5(1), 29–32.
Sulistyo, H., Rahayu, S. S., Winoto, G., & Suardjaja, I. M. (2008). Biodiesel Production from High Iodine Number Candlenut Oil. World Academy of Science, 48, 485–488.
Ubeda, L. C. C., Araújo, A. C., Barbalho, M. S., Bueno, P. C. dos S., Guiguer, É. L., Silva, M. da, Sousa, S. de, Dias, F. de A., Luiza, A. M., Pinheiro, R. A., Marutani, V. H., & Prando, M. (2017). Effects of the Seeds of Aleurites moluccana on the Metabolic Profile of Wistar Rats. The Pharma Innovation Journal, 6(1), 98–103.
Yamlean, P. V., Queljoe, E. De, & Bodhi, W. (2019). Base Variations of the Candlenut Oil Ointment (Aleurites moluccana) and the Healing Potential Test on Wounds in Rabbits. Jurnal Ilmu Kefarmasian Indonesia, 17(2), 232–237.
Published
2021-12-31
How to Cite
LENY, Leny et al.
Aktivitas Anti Luka Bakar dari Gel Minyak Kemiri (Aleurites moluccana L.) terhadap Tikus Putih (Rattus novergicus).
Jurnal Farmasi Udayana, [S.l.], p. 117-120, dec. 2021.
ISSN 2622-4607.
Available at: <https://ojs.unud.ac.id/index.php/jfu/article/view/65402>. Date accessed: 23 nov. 2024.
doi: https://doi.org/10.24843/JFU.2021.v10.i02.p01.
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Articles
