Aktivitas Antibakteri Ekstrak Etanol Daun Kapas (Gossypium barbadense L.) terhadap Staphylococcus epidermidis dan Propionibacterium acnes

  • akhmad khumaidi Jurusan Farmasi, FMIPA Universitas Tadulako, Palu, Indonesia, 94118
  • Arsa Wahyu Nugrahani Jurusan Farmasi, FMIPA Universitas Tadulako, Palu-Indonesia, 94118
  • Febriani Gunawan


Gossypium barbadense L. is one of the plants that has the potential to be developed into an antibacterial agent. This study aims to determine the antibacterial ability of chemical compounds in ethanol extract of Gossypium barbadense L. leaves to Staphylococcus epidermidis and Propionibacterium acnes bacteria which are characterized by the formation of inhibitory zones. Extraction of Gossypium barbadense L. leaves was carried out by maceration using 96% ethanol. Antibacterial activity testing was carried out by agar diffusion method with a cylinder plate technique and the extract was made a concentration series. TLC bioautography and chromogenic reagents are used in the identification of groups of compounds that have antibacterial activity. The results showed that the ethanol extract of Gossypium barbadense L.  leaves gave the greatest inhibition at 70%  extract concentration ie 11.40 ± 0.32 mm against Propionibacterium acnes and 50% extract concentration against Staphylococcus epidermidis bacteria which was 12.28 ± 0.63 mm. The group of compounds that are thought to be responsible for antibacterial activity are flavonoids.

Keywords: Antibacterial, Gossypium barbadense L. Leaves, Propionibacterium acnes, Staphylococcus epidermidis


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Author Biography

Arsa Wahyu Nugrahani, Jurusan Farmasi, FMIPA Universitas Tadulako, Palu-Indonesia, 94118



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How to Cite
KHUMAIDI, akhmad; NUGRAHANI, Arsa Wahyu; GUNAWAN, Febriani. Aktivitas Antibakteri Ekstrak Etanol Daun Kapas (Gossypium barbadense L.) terhadap Staphylococcus epidermidis dan Propionibacterium acnes. Jurnal Farmasi Udayana, [S.l.], p. 52-61, june 2020. ISSN 2622-4607. Available at: <https://ojs.unud.ac.id/index.php/jfu/article/view/57847>. Date accessed: 11 may 2021. doi: https://doi.org/10.24843/JFU.2020.v09.i01.p08.