Review Potensi Tanaman Pegagan (Centella asiatica L.) dalam Dunia Pengobatan Modern
Abstract
For centuries, Asian countries have been using Centella asiatica to treat various types of diseases. Centella asiatica has been associated with its richness in biologically active compounds such as asiatic acid, asiaticoside, madecassic acid, and madecassoside. This literature review aims to explore Centella asiatica and its bioactive compounds towards human health. Based on the review of literature published in the last decade, it was found that asiaticoside obtained from Centella asiatica leaves is a compound with antioxidant, anti-inflammatory, and antimicrobial properties. The activity of asiaticoside plays a crucial role in maintaining human health and is used to prevent and treat various diseases, such as Neurodegenerative Diseases, Cardiovascular Disorders, and Skin Disorders. This literature review provides a fairly comprehensive overview of the benefits of Centella asiatica for human health, particularly summarizing methods and techniques for extracting Centella asiatica and providing an overview of the benefits of Centella asiatica for the treatment of common and chronic diseases, which is expected to be significant for medical literature..
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References
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2. Azis, H. A., Taher, M., Ahmed, A. S., Sulaiman, W., Susanti, D., Chowdhury, S. R., & Zakaria, Z. A. (2017). In vitro and In vivo wound healing studies of methanolic fraction of Centella asiatica extract. South African Journal of Botany, 108, 163–174.
3. Bonfill, M., Mangas, S., Cusidó, R.M., Osuna, L., Piñol, M.T., Palazón, J., 2006. Identification of triterpenoid compounds of Centella asiatica by thin-layer chromatography and mass spectrometry. Biomed. Chromatogr. 20, 151–153. https://doi.org/10.1002/bmc.564
4. Bhandari, P., Kumar, N., Gupta, A. P., Singh, B., & Kaul, V. K. (2007). A rapid RP-HPTLC densitometry method for simultaneous determination of major flavonoids in important medicinal plants. Journal of Separation Science, 30(13), 2092–2096.
5. Brinkhaus, B., Lindner, M., Schuppan, D., & Hahn, E. G. (2000). Chemical, pharmacological and clinical profile of the East Asian medical plant Centella aslatica. Phytomedicine, 7(5), 427–448.
6. Bylka, W., Znajdek-Awiżeń, P., Studzińska-Sroka, E., Dańczak-Pazdrowska, A., & Brzezińska, M. (2014). Centella asiatica in dermatology: an overview. Phytotherapy Research, 28(8), 1117–1124.
7. Cao, S., Wang, W., Nan, F., Liu, Y., Wei, S., Li, F., & Chen, L. (2018). Asiatic acid inhibits LPS-induced inflammatory response in endometrial epithelial cells. Microbial Pathogenesis, 116, 195–199.
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Published
2025-01-10
How to Cite
SODIK, Jajang Japar; SAPUTRO, M Ramadhan; PAHLEVI, Muhamad Reza.
Review Potensi Tanaman Pegagan (Centella asiatica L.) dalam Dunia Pengobatan Modern.
Jurnal Farmasi Udayana, [S.l.], p. 58-68, jan. 2025.
ISSN 2622-4607.
Available at: <https://ojs.unud.ac.id/index.php/jfu/article/view/114802>. Date accessed: 10 jan. 2025.
doi: https://doi.org/10.24843/JFU.2024.v13.i02.p04.
Section
Articles
