ANALISIS TOKSIKOLOGI FORENSIK : KASUS KEMATIAN AKIBAT PENGGUNAAN PROPOFOL

  • Putu Nandya Nandita Udayana

Abstract

Some newspapers (mostly forensics) report cases of abuse, accidental overdoses or criminal purposes with propofol. Propofol is a drug that can reduce anxiety and stress, leading to relaxation and sleep or loss of consciousness. Suicides and intentional and unintentional killings related to the use of propofol have been widely reported. A number of analytical methods have been used to detect and measure the concentration of propofol in biological specimens. Forensic toxicology analysis of death cases related to the use of propofol is carried out from the process of preparing samples (biological specimens), conducting screening tests, ascertainment tests, determination, and interpretation of data.

Downloads

Download data is not yet available.

References

[1] Roussin, A., J. Montastruca, dan M. Lapeyre-Mestre. 2007. Pharmacological and Clinical Evidences on the Potential for Abuse and Dependence of Propofol: A Review of the Literature. Fundamental and Clinical Pharmacology. 21: 459–465.
[2] Vlase, L., D-S. Popa, C. Siserman, D. Zaharia. 2011. High-throughput toxicological analysis of propofol in human whole blood by LC-MS. Romanian Journal of Legal Medicine, Vol. 19 (2).
[3] Levy, Richard J. 2011. Clinical Effects and Lethal and Forensic Aspects of Propofo. Journal of Forensic Science, Vol 56.
[4] Iwersen-Bergmann, S, Rçsner P, Kuhnau HC, Junge M, Schmoldt A. 2001. Death after excessive propofol abuse. Int J Legal Med, 114:248–51.
[5] Procaccianti, P., F. Farè, A. Argo, E. Casagni, S. Arnoldi, S. Facheris, G. L. Visconti, G. Roda, dan V. Gambaro. 2017. Determination of Propofol by GC/MS and Fast GC/MS-TOF in Two Cases of Poisoning. Journal of Analytical Toxicology:1-6.
[6] Clark. 2011. Analysis Drug and Poisons. London : Pharmaceutical Press.
[7] Kirby, R.R., Colaw J.M., Douglas M.M. 2009. Death from Propofol : Accident, Suicide, or Murder?. Anesth Analg, Vol 108 (4).
[8] Wirasuta, I M. A. G. 2008. Analisis Toksikologi Forensik dan Interpretasi Temuan Analisis. Indonesian Journal of Legal and Forensic Sciences, Vol. 1(1).
Published
2019-12-12
How to Cite
NANDITA, Putu Nandya. ANALISIS TOKSIKOLOGI FORENSIK : KASUS KEMATIAN AKIBAT PENGGUNAAN PROPOFOL. Indonesian Journal of Legal and Forensic Sciences (IJLFS), [S.l.], v. 9, n. 2, p. 68 - 75, dec. 2019. ISSN 2657-0815. Available at: <https://ojs.unud.ac.id/index.php/ijlfs/article/view/49820>. Date accessed: 24 nov. 2024. doi: https://doi.org/10.24843/IJLFS.2019.v09.i02.p01.