THE EFFECTIVENES OF ETANOL EXTRACT, PARTITION N-HEKSANA, AND CROMATHOGRAPHY FRACTION OF MOMORDICA CHARANTIA L. TO LOWER BLOOD GLUCOSE LEVEL

  • Ni Luh Putu Kusuma Clara Dewinda
  • I Nyoman Suartha
  • Luh Made Sudimartini

Abstract

This study aims to determine the effectiveness of the ethanol extract, partition n-hexane, and chromatography fractions Momordica charantia L. in lowering blood glucose levels in experimental diabetic male rats.  This study used 25 male rats were divided into five treatment groups P0 (negative control), P1 (positive control), P2 (ethanol extract), P3 (partition n-hexane), and P4 (chromatographic fraction) the variable observed glucose levels blood for 21 days. Blood glucose levels were analyzed on days -1, 0, 4, 11, 18. The bill, which is used in the form of a completely randomized design (CRD). The data obtained and analyzed by using Split in Time. The results showed of giving chromatographic fractions bitter melon 50 mg / kg body weight can reduce blood glucose levels in hyperglycemic rats better than the ethanol extract 200 mg / kg body weight and partition n-hexane 50 mg / kg body weight.

Author Biographies

Ni Luh Putu Kusuma Clara Dewinda

Student of Vetenarian Profession Education Udayana University

I Nyoman Suartha

Laboratory of internal veterinarian medicine, Faculty of Veterinary Medicine

Luh Made Sudimartini

Laboratory of Veterinary Pharmacology and Pharmacy, Udayana University

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Published
2017-08-29
How to Cite
DEWINDA, Ni Luh Putu Kusuma Clara; SUARTHA, I Nyoman; SUDIMARTINI, Luh Made. THE EFFECTIVENES OF ETANOL EXTRACT, PARTITION N-HEKSANA, AND CROMATHOGRAPHY FRACTION OF MOMORDICA CHARANTIA L. TO LOWER BLOOD GLUCOSE LEVEL. Buletin Veteriner Udayana, [S.l.], p. 202-208, aug. 2017. ISSN 2477-2712. Available at: <https://ojs.unud.ac.id/index.php/buletinvet/article/view/31725>. Date accessed: 19 nov. 2019.
Section
Articles