The Effect of Glutaraldehyde Crosslinking on the Morphology of PVA/Chitosan/Collagen Composite Nanofibers

  • Ria Yuliani Udayana University
  • Dewa Ayu Sukma Pranastia Udayana University
  • Ni Nyoman Rupiasih Udayana University http://orcid.org/0000-0003-1268-1416
  • I Wayan Supardi Udayana University
  • K N Suarbawa Udayana University

Abstract

One technique to increase the stability of PVA/chitosan/collagen (PChK) composite nanofibers in water is through cross-linking with glutaraldehyde (GA). In this regard, the aim of this research is to determine the effect of GA cross-linking on the morphology of PChK composite nanofibers. The composite nanofibers used are P8Ch2K2, P8Ch2K4, and P8Ch2K8. The solution used for cross-linking is an Acetone:GA:HCl solution with a ratio of 9:1:0.01 and a reaction time of ±4 hours. Nanofiber characterization was carried out using SEM and analyzed using ImageJ and Origin. It was found that GA cross-linked nanofibers had a larger average fiber diameter, namely with an average increase of 7.54% and more continuous fiber length, namely with an average length increase of 42.06%, compared to nanofibers without GA cross-linking.

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References

[1] A. Suryawan and J. Kinho, Diversity Species of Eboni (Diospyros Spp.) Tulabolo-Pinoguresort, Boganinani Wartabone National Park, North Sulawesi, Widyariset, Vol. 15 no. 2, pp. 2012, 117-126.
[2] F.M. Muhammadi, Teknologi Nano di Indonesia, White Paper Perhimpunan Pelajar Indonesia Se-Dunia. 2020.
[3] Kurniawan dan J. William, Perkembangan dan aplikasi teknologi nano pada industri konstruksi di Indonesia, Tugas Akhir, Universitas Katolik Parahyangan, Bandung.
[4] M. Hulupi dan Haryadi, Sintesis dan Karakterisasi Serat Nano Polivinil Alkohol yang Diikat Silang dengan Glutaraldehid untuk Aplikasi Pembalut Luka, Chimica et Natura Acta, Vol. 6 no. 3, 2018, pp. 101-105.
[5] M. Darmawan, Syamdidi, Y. Yennie dan S. Wibowo, Karakteristik Serat Nano Komposit Chitosan-Polivinil Alkohol (PVA) dari Cangkang Rajungan melalui Proses Electrospinning, JPB Kelautan dan Perikhanyan, Vol. 11 no. 2, 2016, pp. 213-222.
[6] A.Y. Nuryantini, M.M. Munir, T. Suciati dan Khairurrijal, Pembuatan Serat Nano PVA/Chitosan dengan Penambahan Sodium Tripolifosfat (STTP) sebagai Agen Ikatan Sambung Silang, Seminar Nasional Material 2013, Institut Teknologi Bandung.
[7] T. Mutia, E. Novarini dan R.R.S. Gustiani, Preparasi dan Karakterisasi Membran Serat Nano Polivinil Alkohol/Gelatin dengan Antibiotika Topikal Menggunakan Metode Electrospinning, Arena Tekstil, Vol. 35 no. 2, 2020, pp. 95-106.
[8] A. Octavian, Kajian Sifat Fisik-Mekanik dan Antibakteri Plastik Chitosan Termodifikasi Kolagen Limbah Sisik Ikan Kakap Merah, Tugas Akhir, Universitas Negeri Semarang, Semarang, 2015.
[9] A.S. Katili, Struktur dan Fungsi Protein Kolagen, Jurnal Pelangi, Vol. 2 no.5, 2009, pp. 19-29.
[10] P.F.L. Ramadhan, Karakterisasi In Vitro dan In Vivo Komposit Alginat-Poli Vinil Alkohol-ZnO Nano sebagai Wound Dressing Antibakteri, Tugas Akhir, Universitas Airlangga, Surabaya 2012.
[11] I. Hartati dan L. Kurniasari, Kajian Produksi Kolagen dari Limbah Sisik Ikan secara Ekstraksi Enzimatis, Momentum, Vol. 6, no.1, 2010 pp. 33-35.
[12] N. Hamzah, M. Fadhlurrahman, S. Ningsi dan Haeria, Profil Indeks Pengembangan Ikatan-Silang Gelatin-Chitosan, Journal of Pharmaceutical Sciences, Vol. 2 no. 2, 2019, pp. 77-87.
[13] C. Tang, C.D. Saquing, J.R. Harding and S.A. Khan, In Situ Cross-Linking of Electrospun Poly (vinyl alcohol) Nanofibers, Macromoleculs, Vol. 43 no. 2, 2010 pp. 630-637.
[14] A. Hidayati and E. Cahyono, Matrix Composition Effect on the Characteristics of Isopulegol Nanofibers Fabrication by Electrospinning Method, Indonesian Journal of Chemical Science, Vol. 10, no.1, 2021, pp. 49-58.
Published
2024-02-28
How to Cite
YULIANI, Ria et al. The Effect of Glutaraldehyde Crosslinking on the Morphology of PVA/Chitosan/Collagen Composite Nanofibers. BULETIN FISIKA, [S.l.], v. 25, n. 1, p. 56 – 62, feb. 2024. ISSN 2580-9733. Available at: <https://ojs.unud.ac.id/index.php/buletinfisika/article/view/94065>. Date accessed: 21 nov. 2024. doi: https://doi.org/10.24843/BF.2024.V25.i01.p08.