Supplementation of Red Bean (Phaseolus vulgaris L) Extract Decreased Malondialdehyde (MDA) Levels of Stressly Induced Activity of Male Wistar Rats (Rattus norvegicus)

Abstract

This study aims to prove that supplementation of  red bean extract (Phaseolus vulgaris L) decreased malondialdehyde (MDA) levels of stressly induced activity of male wistar rats (Rattus norvegicus). This research was an experimental with pre-test post-test control group design. The rats were randomly divides into 3 groups: negatif control group (P0), positive control group (treated with overtraining and aquades 2ml/P1), and treatment group (treated with supllementation of red bean extract 650 mg/200 g body weight and overtraining/P2). The rats were swam for 45 minutes everyday. Data were analysed by one way anova test. The study showed that MDA level pretest of the each group was 69,70±0,52 mmol/L; 70,12±0,54 mmol/L and 69,59±0,51 mmol/L respectively. MDA level posttest of the each group was 69,66±0,27 mmol/L; 90,08±0,20 mmol/L and 62,85±0,50 mmol/L respectively. From the result of this study, it can be concluded that suplementation of red bean extract (Phaseolus vulgaris L) decreased malondialdehyde (MDA) levels of stressly induced activity of male wistar rats (Rattus norvegicus).

Keyword: red bean (Phaseolus vulgaris L) extract, rats, overtraining, MDA, stress oxidative.