SEORANG PENDERITA HIPOKALSEMIA BERAT OLEH KARENA HIPOPARATIROIDISME DIDAPAT
Abstract
Albeit rare, hypocalcemia might present an acute severe symptom as hypocalcemic seizure, which is documented in ourpatients. Failure in its diagnosis and management will lead to significant morbidity and mortality. Establishing the PTH status,
anorganic-phosphate and magnesium level will enable investigation on possible etiology of hypocalcemia. The overall incidence
of post thyroidectomy hypoparathyroidism and hypocalcemia is about 0.5-3 % worldwide. The pathophysiology are multifactorial,
it is not simply the glands extirpations, as well as its multiple risk factors although operator technique skill is still the
prominent one. We have presented a case of 24 year old female with an acute generalized seizure (hypocalcemic seizure) and
prolonged corrected QT interval due to a severe hypocalcemia secondary to hypoparathyroidism from a total thyroidectomy,
accompanied by acquired hyperthyroidism and a cerebral cortex calcification. Clinical symptoms and total calcium were improved
after intravenous calcium gluconate, followed by oral calcium and calcitriol administrations. However, the ideal therapy
for hypoparathyroidism is still the hormone substitution, either by auto/xeno-transplantations or injections, pending further studies.
PTH level determinations immediately or several hours after surgery and thus oral calcium supplementations might predict
and reduce the incidence of post thyroidectomy hypocalcemia and hypoparathyroidism.
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How to Cite
DHARMAWAN HARJANTO, David; RATNA SARASWATI, Made; SUASTIKA, Ketut.
SEORANG PENDERITA HIPOKALSEMIA BERAT OLEH KARENA HIPOPARATIROIDISME DIDAPAT.
journal of internal medicine, [S.l.], nov. 2012.
Available at: <https://ojs.unud.ac.id/index.php/jim/article/view/3859>. Date accessed: 21 nov. 2024.
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Articles
Keywords
severe hypocalcemia, hypoparathyroidism, post thyroidectomy