SEORANG PENDERITA HIPOKALSEMIA BERAT OLEH KARENA HIPOPARATIROIDISME DIDAPAT

  • David Dharmawan Harjanto
  • Made Ratna Saraswati
  • Ketut Suastika

Abstract

Albeit rare, hypocalcemia might present an acute severe symptom as hypocalcemic seizure, which is documented in our
patients. Failure in its diagnosis and management will lead to significant morbidity and mortality. Establishing the PTH status,
anorganic-phosphate and magnesium level will enable investigation on possible etiology of hypocalcemia. The overall incidence
of post thyroidectomy hypoparathyroidism and hypocalcemia is about 0.5-3 % worldwide. The pathophysiology are multifactorial,
it is not simply the glands extirpations, as well as its multiple risk factors although operator technique skill is still the
prominent one. We have presented a case of 24 year old female with an acute generalized seizure (hypocalcemic seizure) and
prolonged corrected QT interval due to a severe hypocalcemia secondary to hypoparathyroidism from a total thyroidectomy,
accompanied by acquired hyperthyroidism and a cerebral cortex calcification. Clinical symptoms and total calcium were improved
after intravenous calcium gluconate, followed by oral calcium and calcitriol administrations. However, the ideal therapy
for hypoparathyroidism is still the hormone substitution, either by auto/xeno-transplantations or injections, pending further studies.
PTH level determinations immediately or several hours after surgery and thus oral calcium supplementations might predict
and reduce the incidence of post thyroidectomy hypocalcemia and hypoparathyroidism.

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Author Biographies

David Dharmawan Harjanto
Department of Internal Medicine, Makati Medical Center, the Philippines
Made Ratna Saraswati
Bag/SMF Ilmu Penyakit Dalam FK Unud/RSUP Sanglah Denpasar
Ketut Suastika
Bag/SMF Ilmu Penyakit Dalam FK Unud/RSUP Sanglah Denpasar
How to Cite
DHARMAWAN HARJANTO, David; RATNA SARASWATI, Made; SUASTIKA, Ketut. SEORANG PENDERITA HIPOKALSEMIA BERAT OLEH KARENA HIPOPARATIROIDISME DIDAPAT. journal of internal medicine, [S.l.], nov. 2012. Available at: <https://ojs.unud.ac.id/index.php/jim/article/view/3859>. Date accessed: 02 nov. 2024.
Section
Articles

Keywords

severe hypocalcemia, hypoparathyroidism, post thyroidectomy

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