HUBUNGAN JUMLAH FOLIKEL ANTRAL DENGAN RESPONS OVARIUM TERHADAP STIMULASI OVULASI

Abstract

Recent studies show there is possibility to predict ovarian response to ovulation stimulation. Several possible
predictor factors are age, ovarian volume, antral follicle count (AFC), ovarian stroma blood flow, and hormonal
markers like Follicle Stimulating Hormone (FSH), Estradiol (E2) and Inhibin B. AFC is a simple examination for
ovarian reserve. Compared with hormonal markers, AFC more simply, relatively less costly and only using ultrasound
machine, which widely available and the result could be obtained in timely manner. To understand relationship
between AFC and ovulation stimulation response. All women who joined IVF program with short protocol stimulation
from January 2005 until May 2006 were enrolled into the study. Data collected were AFC day two, mature follicle
count, total oocyte count, mature oocyte count, and total gonadotrophin dose. Data were analyzed with Kendall’s
correlation test to show relationship. This study shows statistically significant correlations between AFC with mature
follicle count (r=0,329; p=0,037), total oocyte count (r=0,506; p=0,001), mature oocyte count (r=0,492; p=0,002), and
total gonadotrophin dose (r=-0,477; p=0,002). This study shows there are statistically significant correlations between
AFC with ovarian response to ovulation stimulation and the cutoff point of AFC is 4,5.