ANTIOXIDANT ACTIVITY TEST OF ANDROGRAPHOLIDE IN BITTER HERBS USING DPPH SCAVENGING

  • Ni Made Pitri Susanti Udayana University
  • Ni Kadek Warditian Udayana University
  • I Made Agus Gelgel Wirasuta Udayana University

Abstract

Abstract Bitter herbs (Sambiloto) have many pharmacological activities including antioxidant, antidiabetic, anticancer,


antihyperlipidemic and anti-inflammation. Andrographolide is a diterpene compounds contained in bitter herbs. It is known that


andrographolide compound responsible for the pharmacological activity of the bitter herbs. This study investigated DPPH free


radical scavenging activity from andrographolide diterpene lactone. This study was initiated with the isolation of


andrographolide compound from bitter herbs and then testing their DPPH free radical scavenging. The results suggested that


andrographolide had IC50 value of 5.45 mg. This means andrographolide has 50% DPPH inhibition effect, i.e 5.45 mg.

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Author Biographies

Ni Made Pitri Susanti, Udayana University

Department of Pharmacy, Faculty of Mathematics and Natural Sciences 1

Ni Kadek Warditian, Udayana University

Department of Pharmacy, Faculty of Mathematics and Natural Sciences 2

I Made Agus Gelgel Wirasuta, Udayana University

Department of Pharmacy, Faculty of Mathematics and Natural Sciences 3

References

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17
Published
2017-02-01
How to Cite
SUSANTI, Ni Made Pitri; WARDITIAN, Ni Kadek; WIRASUTA, I Made Agus Gelgel. ANTIOXIDANT ACTIVITY TEST OF ANDROGRAPHOLIDE IN BITTER HERBS USING DPPH SCAVENGING. Journal of Health Sciences and Medicine, [S.l.], v. 1, n. 1, p. 9-11, feb. 2017. ISSN 2622-0555. Available at: <https://ojs.unud.ac.id/index.php/jhsm/article/view/34806>. Date accessed: 04 nov. 2024. doi: https://doi.org/10.24843/JHSM.2017.v01.i01.p03.