KASUS AGITASI AKIBAT PEMAKAIAN MEPHEDRONE
Abstract
Mephedrone or 4-Methylmethcathinone is one type of NPS (New Psychoactive Substance) which is included in the katinon derivative. Mephedrone has been banned in Indonesia and in other countries such as the Netherlands. Mephedrone is used as a recrerational drug that can increase enthusiasm for its users. Misuse of mephedrone can cause toxicity to death for its users. In reviewing this article we will summarize the cases of mephedrone abuse in Indonesia, the pathway for mephedrone synthesis, the pharmacological, pharmacokinetic and pharmacodynamic effects of mephedrone and forensic toxicology analysis on cases of misuse of mephedrone compounds.
Downloads
References
[2] BNN. 2016. Daftar Nama Zat NPS yang Sudah Teridentifikasi Di Indonesia, viewed 28 Februari 2019, http://lab.bnn.go.id/nps_alert_system/12.%20Lampiran%20zat%20NPS%20terdeteksi%20di%20Indonesia.php
[3] Camilleri,A., M. R. Johnston, M. Brennan, S. Davis, D. G. Caldicott. 2010. Chemical analysis of four capsules containing the controlled substance analogues 4-methylmethcathinone, 2-fluoromethamphetamine, alpha phthalimidopropiophenone and N-ethylcathinone. Forensic Sci. Int. Vol. 197, pp: 59.
[4] Dargan, P.I., R. Sedefov, A. Gallegos and D.M. Wood. 2011. The pharmacology and toxicology of the synthetic cathinonemephedrone (4-methylmethcathinone). Drug Testing and Analysis. 3 :454-463.
[5] Gibbons, S., M. Zloh. 2010. An analysis of the ‘legal high’ mephedrone. Bioorg. Med. Chem. Lett.Vol.20, pp: 4135.
[6] Lusthof, K.J., R. Oosting, A. Maes, M. Verschraagen, A. Dijkhuizen, and A.G.A.Sprong. 2011. A case of extreme agitation and death after the use of mephedrone in The Netherlands. Forensic Science international. 206: 93-95.
[7] Patuwondo, M. 2018. Indonesia : Narkoba dalam Angka Tahun 2017. Jurnal Data Puslitdatin.
[8] Schifano, F., A. Albanese, S. Fergus, J.L. Stair, P. Deluca, O. Corazza, Z. Davey, J.Corkery, H. Siemann, N. Scherbaum, M. Farre, M. Torrens, Z. Demetrovics, A.H. Ghodse, P.W. Mapping, and R.R. Groups. 2011. Mephedrone (4-methylmethcathinone; ‘meow meow’): chemical, pharmacological and clinical issues. Psychopharmacology. 214:593-602.
[9] Wirasuta, I M. A. G. 2008. Analisis Toksikologi Forensik dan Interpretasi Temuan Analisis. Indonesian Journal of Legal and Forensic Sciences, Vol. 1(1).