RADIONUCLIDE SCANNING WITH I-123 IN GRAVES DISEASE

Abstract

Graves’ disease is the most common form of thyrotoxicosis which caused by
autoimmune that attacks the thyroid gland. This disease will lead such following
syndromes: thyrotoxicosis, goiter, ophthalmopathy, dermopathy. The sensitive TSH
assay is the single best screening test for hyperthyroidism, and in most outpatient
clinical situations. But when there is a doubt to distinguish diffuse toxic goiter (Graves’
disease) from autonomous toxic nodule (Plummer’s disease), radioinuclide scanning can
be performed. I-123 is one of the preferable radiosisotope because it can produce clear
image and short enough half-life, although the price is expensive.