CHARACTERISTICS AND RISK FACTORS OF BREAST CANCER AT THE CENTRAL GENERAL HOSPITAL PROF. DR. I G.N.G. NGOERAH IN 2022
- Nadya Zalfa Aqilah Bachelor of Medicine, Faculty of Medicine, Udayana University
- Ni Gusti Ayu Agung Manik Yuniawaty Wetan, Sp.B(K)Onk Surgical Oncology Subdivision, Department of Surgery, Faculty of Medicine, Udayana University, Sanglah General Hospital, Denpasar, Bali, Indonesia
- I Gede Budhi Setiawan, Sp.B(K)Onk Surgical Oncology Subdivision, Department of Surgery, Faculty of Medicine, Udayana University, Sanglah General Hospital, Denpasar, Bali, Indonesia
- Putu Anda Tusta Adiputra, Sp.B(K)Onk, FinaCS, FICS Surgical Oncology Subdivision, Department of Surgery, Faculty of Medicine, Udayana University, Sanglah General Hospital, Denpasar, Bali, Indonesia http://orcid.org/0000-0003-2676-8037
Abstract
Breast cancer is a disease that has high mortality in women throughout the world. Breast cancer has characteristics and risk factors that influence the incidence of breast cancer. The research method uses a retrospective descriptive study and uses secondary data, namely medical records at the Central General Hospital Prof. Dr. I G.N.G. Ngoerah in 2022. Of the total 551 samples, only 319 samples had complete medical records. The variables studied were age, clinical stage, histopathological type, biopsy grade, subtype, lesion location, menopausal status, age at menarche, age at menopause, family history of cancer, parity, breastfeeding history, history of hormonal therapy, and nutritional status in terms of BMI. The results showed that of the 319 breast cancer patients, 77.4% were ?45 years old, 38.2% were stage IIIB, 86.2% were invasive ductal carcinoma, 56.4% were grade III, 36.4% were luminal B subtype, 41.4% were in the menopausal phase, the average age of menarche was 13 years old, 42% had menopause in the 45-50 year age range, 4.4% had a family history of cancer, 73% were multiparous, 91.5% had a history of breastfeeding, 23.8% had a history of hormonal therapy, and 37.3% had a normal BMI nutritional status.
Keywords: Characteristics, Risk Factors, Breast Cancer
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Author Biographies
Nama Lengkap : dr. Ni Gusti Ayu Agung Manik Yuniawaty Wetan, Sp.B(K)Onk
Jenis Kelamin : Perempuan
Tempat / Tanggal Lahir : Denpasar, 11 Juni 1977
Status Pekerjaan : PNS
NIP. : 19770611 201012 2 002
Gol / Pangkat : IIIb / Penata Muda TK. I
Alamat Tempat Bekerja : Sub. Bagian Bedah Onkologi
Bag/SMF Ilmu Bedah FK UNUD/RSUP Sanglah
Jl. Diponegoro No. 1 Denpasar - Bali (80114)
Telp / Fax : (0361) 241906
Email : manikyw@gmail.com
Alamat Tempat Tinggal : Jl. Majapahit No.2 Dusun Mekar Sari, Dauh Puri, Denpasar – Bali
Telp : (0361) 426102, HP : 08123214075, 08123963764
Status : Belum Menikah
PENDIDIKAN
SDN 17 Dauh Puri, lulus tahun : 1989
SMPN 1 Denpasar, lulus tahun : 1992
SMAN 1 Denpasar, lulus tahun : 1995
Dokter Umum FK UNAIR Surabaya, lulus tahun : 2002
PPDS I Ilmu Bedah Umum FK UNUD Denpasar, lulus tahun : 2010
Spesialis Bedah Konsultan Onkologi FK UNUD Denpasar, lulus tahun : 2015
RIWAYAT PEKERJAAN
- Dokter spesialis bedah di RS Tarakan, bulan Juni 2010 – April 2011.
- Staf Sub. Bagian Bedah Onkologi, Bag/SMF Ilmu Bedah FK UNUD/RSUP Sanglah Denpasar, tahun 2011 - sekarang.
ORGANISASI PROFESI
- Anggota IDI (Ikatan Dokter Indonesia)
- Anggota IKABI (Ikatan Ahli Bedah Indonesia)
- Anggota PABI (Persatuan Ahli Bedah Umum Indonesia)
- Anggota PERABOI (Perhimpunan Ahli Bedah Onkologi Indonesia)
PEMBICARA
- The Role of Oxycodone for Cancer Pain Management (SSOGS, Symposium : Management Of Soft Tissue Sarcoma : Where Are We ?,And Symposium On Breast Cancer : Hormonal And Targeted Therapy , Workshop : Local Flaps In Cancer Surgery) February th. 2017
- The Role of Opioid in Cancer Pain Management (SSOGS, Workshop and Symposium : Mastering Chemotherapy in Solid Tumors) September th.2017
- New Insight in Management of Induce Chemotherapy Neutropenia (SSOGS, Workshop Modified Radical Mastectomy, Chemotherapy Dan Symposium Breast Cancer Management Update) September th. 2018
IDENTITAS
Nama : dr. I Gede Budhi Setiawan, Sp.B(K)Onk
Jenis Kelamin : Laki - Laki
Tempat / Tanggal Lahir : Denpasar, 22 Mei 1971
Alamat Tempat Bekerja : Sub. Bagian Bedah Onkologi, Bag/SMF Ilmu Bedah
FK UNUD/RSUP Sanglah
Jl. Diponegoro No. 1 Denpasar - Bali (80114)
Telp / Fax : (0361) 241906
Email : dhiwans@hotmail.com
Alamat Tempat Tinggal : Jl. Trijata II / 2 Denpasar - Bali
Telp. : (0361) 223030, HP : 08123923956
Status : Kawin
Nama Istri : dr. Ni Made Suryanadi, Sp.M
Nama Anak-anak : Ni Luh Putu Pritha Dewi Karunika
Ni Made Laksmi Dewi Paramitha
Komang Gayatri Mahadewi Setiawan
PENDIDIKAN
SD Katolik Swastiastu Lulus th : 1984
Sekolah Menengah Pertama 5 Semarang Lulus th : 1987
Sekolah Menengah Atas 3 Semarang Lulus th : 1990
Dokter Umum FK UNDIP Semarang Lulus th : 1997
PPDS I Ilmu Bedah Umum FK UNUD Denpasar Lulus th : 2006
Spesialis Bedah Konsultan Onkologi FK UNUD Denpasar Lulus th : 2009
RIWAYAT PEKERJAAN
- Puskesmas Petang II, Kecamatan Petang – Badung, tahun 1997 – 2000
- Bagian Bedah RSUD Bima - NTB, tahun 2006
- Program Pendidikan Dokter Spesialis I Ilmu Bedah Umum FK UNUD/RSUP Sanglah, tahun 2001 - 2006
- Staf Sub. Bagian Bedah Onkologi Bag/SMF Ilmu Bedah FK UNUD/RSUP Sanglah Denpasar - Bali, tahun 2009 - sekarang
ORGANISASI PROFESI
- Anggota IDI (Ikatan Dokter Indonesia)
- Anggota IKABI (Ikatan Ahli Bedah Indonesia)
- Anggota PABI (Persatuan Ahli Bedah Umum Indonesia)
- Anggota PERABOI (Perhimpunan Ahli Bedah Onkologi Indonesia)
- Anggota POI (Perhimpunan Onkologi Indonesia)
- Anggota Instruktur ATLS
- Anggota Instruktur Perioperative Course
Name : dr. Putu Anda Tusta Adiputra, Sp.B(K)Onk, FinaCS, FICS
Specialization : General Surgery and Oncology Surgery
Address : Surgical Oncology Subdivision, Department of Surgery, Faculty of Medicine, Udayana University, Sanglah General Hospital, Denpasar, Bali, Indonesia
Home : Fujihome Renon Residence Kav 32, Jl. Tukad Balian Renon, Denpasar
Telephone : (+62-85) 101403071, (+62-81) 23826430
Date of Birth : 21 June 1975
Nationality : Indonesian
Marital Status : Married with two son and one daughter
Place of Birth : Denpasar, Bali, Indonesia
Educational Background:
- SDN no. 6 Dauh Puri Denpasar, 1981-1987 (Elementary School).
- SMPN 1 Denpasar, 1987-1990 (Junior High School)
- SMAN 1 Denpasar, 1990-1993 (Senior High School).
- Medical Faculty, Udayana University, Denpasar, 1993-1999.
- General Surgeon Trainee, Udayana University, Sanglah General Hospital, 2001- 2006
- Surgical Oncology Trainee, Udayana University, Sanglah General Hospital, 2007 - 2010
Paper Delivered at Conferences:
- Mesenteric Lymphangioma in a Child. P2B2 PABI ke-2, Surabaya, 8-11 December 2004.
- Validity of Fine Needle Aspiration Biopsy of Salivary Gland Tumors. Konas II PABI, Batam, 2-5 September 2006.
- Eccrine Spiradeno Carcinoma. PIT PABI X, Balikpapan, 21-23 March 2013
- Follicular Adenoma Thyroid in A Eleven Years Old Male. 19th Annual Scientific Meeting of Indonesian Surgeon Association (IKABI), Semarang, 20-24 August 2013.
- Leiomioma Payudara yang Tumbuh Bersama dengan Borderline Phylloides Tumor (Case Report). 19th Annual Scientific Meeting of Indonesian Surgeon Association (IKABI), Semarang, 20-24 August 2013.
- Tracheal Resection and Anastomosis in Papillary Thyroid Carcinoma with Tracheal Infiltration (A Case Report). International College of Surgeons Asia Pacific Federation Congress 2013 in Commemoration of 60th Anniversary of ICS Thailand Section, Bangkok, 5-7 December 2013.
- Secretory Breast Cancer: A Case Report. Konas IV PABI, Bandung, 13-17 May 2014.
- Case Report: Osteosarcoma in Maxilla. Konas IV PABI, Bandung, 13-17 May 2014.
- Trend in Diagnosis and Treatment of Breast Cancer in Elderly of Balinese Population: Analysis of The Local Cancer Registry. 2nd Asia - Pacific Conference of the International Society of Geriatric Oncology. Singapore, 11-12 July 2014.
- Histology and Biologic Profile of Breast Cancer in Elderly of Balinese Population. 2nd Asia - Pacific Conference of the International Society of Geriatric Oncology. Singapore, 11-12 July 2014.
- Extravasation of Intravenous Chemotherapy in RSUP Sanglah Denpasar. The 39th Biennial World Congress of The International College of Surgeons. Bali, 20-25 October 2014.
- Sociodemographic and Clinical Profile of Patients with Surgical Wound Debridement at BIMC Hospital Nusa Dua, A Descriptive Study. The 39th Biennial World Congress of The International College of Surgeons. Bali, 20-25 October 2014.
- Difference in Breast Cancer Diagnosis and Treatment by Age among Balinese Woman, Analysis of The Local Cancer Registry. The 39th Biennial World Congress of The International College of Surgeons. Bali, 20-25 October 2014.
- Biologic characteristic of breast cancer in Balinese elderly women. The 39th Biennial World Congress of The International College of Surgeons. Bali, 20-25 October 2014.
- Shark Bite on Surfers in Bali: A Serial Cases Report. The 39th Biennial World Congress of The International College of Surgeons. Bali, 20-25 October 2014.
- Squamous Cell Carcinoma of SCALP - Reconstruction with Double Rotational Flap: A Serial Case Reports. The 39th Biennial World Congress of The International College of Surgeons. Bali, 20-25 October 2014.
- Karakteristik Penderita Kanker Tiroid di RSUP Sanglah Denpasar Periode Januari 2010-Desember 2013. Kongres Nasional (Konas) PEBKLI I 2015. Surabaya, 21-22 February 2015.
- Evaluation Use of Totally Implantable Vascular Access Port for Chemotherapy During Five Years in Sanglah General Hospital-Denpasar. 20th National Congress of Indonesian Surgeons Associations (MABI XX) in conjunction with 2nd International College of Surgeons-Indonesia Section (ICS INA) Meeting. Surabaya, 20-22 August 2015
Paper on Scientific Journal:
- Adiputra, P.A.T., Manuaba, I.B.T.W., Saputra, H., 2007. Validitas Diagnosis Fine Needle Aspiration Biopsy (FNAB) pada Tumor Kelenjar Ludah. Medicina, Vol. 38, No. 2, 113-117.
- Adiputra, P.A.T., Sukerena, I N., 2007. Mesenteric Lymphangioma in a Child. Jurnal Ilmu Bedah Indonesia, Vol. 35, No. 1, 23-26.
- Adiputra, P.A.T., 2008. Splinter, Masalah dan Solusinya. Medicina, Vol. 39, No. 2, 105-107.
- Mirah-K, I.G.A., Adiputra, P.A.T., 2012. Komplikasi, Pencegahan dan Penanganan Ekstravasasi Agen Kemoterapi. E-Jurnal Medika Udayana, Vol. 1, No. 1.
- Paramitha, I M.B.A., Adiputra, P.A.T, 2013. Cryosurgery dalam Penatalaksanaan Veruka. E-Jurnal Medika Udayana, Vol. 2, No. 1.
- Vitriasari, N.W.A., Adiputra, P.A.T., Maliawan, S., 2012. Mastitis Tuberkulosis. E-Jurnal Medika Udayana, Vol. 2, No. 2.
- Widyastuti, R., Adiputra, P.A.T., Maliawan, S., 2013. Core Needle Biopsy pada Tumor Payudara. E-Jurnal Medika Udayana, Vol. 2, No. 2.
- Mulia, Y.A., Adiputra, P.A.T., 2013. Teknik Guillotine dan Gomco Clamp pada Sirkumsisi. E-Jurnal Medika Udayana, Vol. 2, No. 3.
- Winangun, I M.A.W., Adiputra, P.A.T., Maliawan, S., Kawiyana, K.S., 2013. Penatalaksanaan Hemoroid Interna Menggunakan Teknik Rubber Band Ligation. E-Jurnal Medika Udayana, Vol. 2, No. 10.
- Puspita, N.K.H., Adiputra, P.A.T., 2014. Tingkat Pengetahuan dan Perilaku Ibu-ibu Pembinaan Kesejahteraan Keluarga Desa Adat Legian tentang Pemeriksaan Payudara Sendiri. E-Jurnal Medika Udayana, Vol. 3, No. 10.
- Adiputra, P.A.T., Manuaba, I.B.T.W., 2014. Correlation of Parathyroid Hormone-1 Receptor Expression to Bone Metastasis of Breast Carcinoma Patients. Bali Medical Journal (BaliMed.J.), Vol. 3, No. 1, 31-35.
- Prayudi, P.K.A., Permatasari, A.Y., Adiputra, P.A.T., 2014. Histology and Biologic Profile of Breast Cancer in Elderly of Balinese Population. Journal of Geriatric Oncology, Vol. 5, Supplement 1, S9. (Abstract only).
- Permatasari, A.Y., Prayudi, P.K.A., Adiputra, P.A.T., 2014. Trend in Diagnosis and Treatment of Breast Cancer in Elderly of Balinese Population: Analysis of The Local Cancer Registry. Journal of Geriatric Oncology, Vol. 5, Supplement 1, S10. (Abstract only).
- Dewi, I G.A.M.P., Adiputra, P.A.T., 2015. Karakteristik Penderita Kanker Tiroid di Bagian Bedah Onkologi RSUP Sanglah Denpasar Tahun 2009-2012. E-Jurnal Medika Udayana, Vol. 4, No. 3.
- Permatasari, Y., Prayudi, P.K.A., Adiputra, P.A.T., 2015. Eccrine Spiradenokarsinoma: Keganasan Adnexa Kulit yang Jarang. CDK-234, Vol. 42 no. 11.
Course/Workshop:
- USG for Trauma Course, Jakarta, April 2001.
- Advanced Trauma Life Support, Denpasar, May 2001.
- Perioperative Course, Denpasar, September 2004.
- Definitive Surgical Trauma Care Course, Bandung, April 2006.
- Basic Laparoscopic Course, Surabaya, May 2006.
- Workshop Pemanfaatan Teknik Biologi Molekuler di Bidang Kedokteran, Denpasar, January 2007.
- Course on Tumor Imunology, Denpasar, March 2007.
- Total Nutritional Therapy Course, Denpasar, May 2007.
- Aplication of Biomolecular Sciences in Surgical Oncology Course, Yogyakarta, July 2007.
- Kursus Biologi Molekuler & Imunologi, Yogyakarta, February 2008.
- Training of the Trainer Total Nutritional Therapy Course, Bandung, April 2008.
- Total Nutritional Therapy Course, Tabanan, May 2008 (Instructor).
- Kursus Keterampilan Bedah Dasar, Tabanan, November 2008 (Instructor).
- Total Nutritional Therapy Course, Tabanan, December 2008 (Instructor).
- Kursus Pelatihan untuk Pelatih, Kolegium Ilmu bedah Indonesia, Denpasar, April 2009.
- Introduction to Safe Surgical Skill Course, Tabanan, April 2009 (Instructor).
- Total Nutritional Therapy Course, Tabanan, November 2009 (Instructor).
- Total Nutritional Therapy Course, Tabanan, December 2009 (Instructor).
- Total Nutritional Therapy Course, Tabanan, April 2011 (Instructor).
- Breast Ultrasound & Ultrasound Guided Breast Biopsy Course (Hands-on Training), Bali, January 2011.
- Hepatocellular Carcinoma Workshop, Sanur-Bali, February 2011.
- Total Nutritional Therapy Course, Tabanan, April 2011 (Instructor).
- TOT Deteksi Dini Kanker Leher Rahim dan Kanker Payudara, Kementerian Kesehatan Republik Indonesia, Jakarta, May 2011.
- Training of Trainers (TOT) on Procedural and Surgical Skill Teaching (ICTEC), Jakarta, June 2011.
- Total Nutritional Therapy Course, Tabanan, April 2012 (Instructor).
- Total Nutritional Therapy Course, Tabanan, April 2013 (Instructor).
- Workshop Nasional Penguji dan Pelatih SP OSCE UKDI, Denpasar, February 2013.
- Chemo-Port Implantation (Celsite) Workshop on Indonesia Vascular Update IV, Bandung, November 2013.
- Marathon Workshop and Hands-on Experience on Breast and Thyroid Cancer Surgery: Refining Operative Technique, Denpasar, November 2013.
- Alan Walker Cancer Care Centre-Breast Cancer Care Workshop, Darwin, February 2014.
- 14th Fresenius Kabi Advanced Nutrition Course Asia, Taipei, March 2014.
- Training the Trainers Course by The Royal College of Surgeons of Edinburgh and The College of Surgeons of Indonesia, Malang, May 2015.
- Direct Assessment of Complex Surgical Procedures Course by The Royal College of Surgeons of Edinburgh and The College of Surgeons of Indonesia, Malang, May 2015.
- Workshop Breast Implant at Muktamar X Peraboi, Malang, October 2015.
Speaker:
- Simple Wound Debridement and Suturing, RTD and Workshop, BIMC Hospital, Kuta, 1 December 2008.
- Pendidikan Kedokteran Berkelanjutan (PKB) XVII Ilmu Penyakit Dalam FK Unud/RSUP Sanglah Denpasar, Aston Convention Centre, Denpasar, 29-31 October 2009.
- Konker dan Temu Riset Nasional Peraboi, Sanur Paradise Plaza Hotel, Bali, 30 October 2009 – 1 November 2009.
- Bali Endocrine Update (BEU)-VII, Bali Geriatric Update Symposium (BAGUS)-IV & Workshop, RSUP Sanglah, Denpasar, 28-29 April 2010.
- Workshop & Hands-on Experience on Thyroid Surgery, Sanglah General Hospital, Denpasar, 28-29 July 2011.
- Seminar Pain Management, RSUP Sanglah, Denpasar, 21 December 2011.
- Breast Cancer Awareness Campaign, Bala Keselamatan Korps I, Denpasar, 23 February 2012.
- Continuing Professional Development: Malignancy yang Berhubungan dengan Pekerjaan, FK Unud, Denpasar, 25 February 2012.
- Workshop Practical Chemotherapy of Breast and Colorectal Cancer, Sanglah Hospital, Denpasar, 2 June 2012.
- Bali Infectious Diseases Symposium-4, Inna Grand Bali Beach, Sanur-Bali, 14-15 September 2012.
- Indonesian Society of Oncology Annual Scientific Meeting Bali 2012, Inna Grand Bali Beach, Sanur-Bali, 28-29 September 2012.
- Continuing Professional Development: Onkologi Tiroid, FK Unud, Denpasar, 30 March 2013.
- Cancer Pain Forum, All Season Hotel, Denpasar, 13 December 2013.
- International Joint Symposium 8th Bali Geriatric Update Symposium-21st Annual Scientific Meeting Japan Society of Haemorheology-Kobe Women’s University, Denpasar, 24 Agustus 2014.
- Workshop Perawatan Pasien Pasca Insersi Chemo-Port. Sanglah General Hospital, Denpasar, 8 March 2015.
- Short Symposium and Workshop: “Practical Guidelines for Chemotherapy Side Effect”, Denpasar, 28 March 2015.
- Temu Riset Nasional II Peraboi: “Menuju Penelitian Multisenter”, Tuban-Bali, 14-15 August 2015.
Working Experience:
- Working as General Surgeon at Trauma Centre, Sanglah General Hospital, January-June 2007.
- Working as Surgical Oncologist at Sanglah General Hospital, 2010- now.
- Working as Medical Student Education Coordinator in Surgery Department, Medical Faculty, Udayana University, 2011-2014.
- Working as Secretary of General Surgeon Training Program, Medical Faculty, Udayana University, 2014-now.
Membership/Fellowship:
- Member of Indonesian Medical Association (IDI)
- Fellow of Indonesian General Surgeon Society (IGSS/FInaCS)
- Fellow of Indonesian Surgeon Association (FISA)
- Fellow of Indonesian Surgical Oncology Society (PERABOI)
- Member of Indonesian Society of Oncology (POI)
- Member of Indonesian Palliative Association (MPI)
- Fellow of International College of Surgeon (FICS)