COVID-19 DAN SISTEM KARDIOVASKULAR: SEBUAH TINJAUAN PUSTAKA

  • Leonardo Alpha Diaz Program Studi Sarjana Kedokteran dan Profesi Dokter, Fakultas Kedokteran, Universitas Udayana, Bali, Indonesia
  • Anak Agung Istri Nanda Pramesthi Cahyani Program Studi Sarjana Kedokteran dan Profesi Dokter, Fakultas Kedokteran, Universitas Udayana, Bali, Indonesia
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Abstrak

ABSTRACT


Introduction: In 2019, the first case of SARS-Cov-2 infection was reported in Wuhan, China. SARS-Cov-2 virus has rapid transmission through droplets or aerosols, so that the virus spreads easily all over the world. Up to now, global COVID-19 cases have reached hundreds of millions of cases. COVID-19 itself has been reported to be associated with the cardiovascular system.


Discussion: SARS-Cov-2 virus infect human body through binding to angiotensin converting enzyme 2 (ACE2) receptor. Aside from the lung, ACE2 receptors can be found in some other organs, such as heart, liver, kidney, etc. Therefore, COVID-19 patients frequently have extrapulmonary clinical manifestations. Several pathological conditions in COVID-19 patients (excess immune response, endothelial dysfunction and coagulation disruption, or direct infection of SARS-Cov-2 virus) have a potential to cause damage in cardiovascular system.


Conclusion: COVID-19 is tightly associated with cardiovascular system. Comorbidity in the cardiovascular system increases the susceptibility of someone to get COVID-19 and worsens the disease progression. The other way around, COVID-19 also potentiates to trigger cardiovascular diseases.

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2023-04-11
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DIAZ, Leonardo Alpha; CAHYANI, Anak Agung Istri Nanda Pramesthi. COVID-19 DAN SISTEM KARDIOVASKULAR: SEBUAH TINJAUAN PUSTAKA. Essence of Scientific Medical Journal, [S.l.], v. 20, n. 2, p. 27-37, apr. 2023. ISSN 2655-6472. Tersedia pada: <https://ojs.unud.ac.id/index.php/essential/article/view/84158>. Tanggal Akses: 19 may 2024 doi: https://doi.org/10.24843/essential.v20i2.84158.