Prevalence and Hemodynamic Outcome of Dengue Shock Syndrome in Children Attending the Department of Pediatrics, Dr. Soetomo General Hospital
Abstract
Abstract
The prevalence of Dengue infection has increased markedly worldwide. Dengue shock syndrome (DSS) is a severe manifestation of dengue virus infection. Higher mortality of DSS was found in children. This study’s aim was to portray prevalence and hemodynamic outcome in children attending the department of pediatric in Dr. Soetomo General Hospital. A Descriptive Retrospective study of children aged <15 years old with DSS was performed and evaluated from 2013-2016. The samples were divided into 5 groups, aged <1 years old, 1-2 years old, 3-5 years old 6-11 years old and 12-15 years old. Data were taken secondarily and calculated with Microsoft Excel 2010. The most common findings were prevalence of DSS in 6-11 years old group and mortality rate in <1 years old group. This can be seen as in the hemodynamic outcome; the average HR was higher in aged group 1-2 years old while RR was higher in group under 1-year-old. Meanwhile, the average blood pressure, PP, and MAP were lower in children under 2 years old. The hemodynamic outcome varies on each group based on age. Incidence of DSS remained high in older children but mortality rates were high in younger children.
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References
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27. Pizarro-Torres D. Dengue With Severe Plasma Leakage: A New Monitoring Approach. Acta Méd Costarric. 2016; 58(3): 115-121.
28. Han J, Ren HQ, Zhao QB, Wu YL, Qiao ZY. Comparison of 3% and 7.5% Hypertonic Saline in Resuscitation After Traumatic Hypovolemic Shock. Shock. 2015 Mar;43(3):244-9. doi: 10.1097/SHK.0000000000000303.
29. Balmaseda, A., Hammond, SN., Pérez, MA., dkk. Short report: assessment of the World Health Organization scheme for classification of dengue severity in Nicaragua. Am J Trop Med Hyg. 2005;73(6):1059-62.
30. Cao, XT., Ngo, TN., Wills, B., dkk. Evaluation of the World Health Organization standard tourniquet test and a modified tourniquet test in the diagnosis of dengue infection in Viet Nam. Trop Med Int Health. 2002;7(2):125-32.
31. Opreanu RC, Arrangoiz R, Stevens P, Morrison CA, Mosher BD, Kepros JP. Hematocrit, systolic blood pressure and heart rate are not accurate predictors for surgery to control hemorrhage in injured patients. Am Surg. 2010 Mar;76(3):296-301.
32. Victorino GP, Battistella FD, Wisner DH. Does tachycardia correlate with hypotension after trauma?. J Am Coll Surg. 2003 May;196(5):679-84. doi: 10.1016/S1072-7515(03)00128-5
2. World Health Organization. CD Risk Assessment; DF, DBD and DSS in Indonesia, http://www.who.int/diseasecontrol_emergencies/guidelines/Dengue_ind_risk%20assess.pdf; 2005 [accessed 12 February 2017].
3. Departemen Kesehatan RI. Kemenkes Terima Laporan Peningkatan Kasus DBD di Jawa Timur, http://www.depkes.go.id/article/view/15013000002/kemenkes-terima-laporan-peningkatan-kasus-dbd-di-jawa-timur.html#sthash.k81F01M4.dpuf; 2015 [accessed 12 February 2017].
4. Raihan, Hadinegoro SRS, Tumbelaka AR. Faktor Prognosis Terjadinya Syok pada Demam Berdarah Dengue. Sari Pediatr. 2010;12(1):47–52.
5. Dejnirattisai, W., Jumnainsong, A., Onsirisakul, N., dkk. Cross-reacting antibodies enhance dengue virus infection in humans. Science. 2010;328(5979):745-8. doi: 10.1126/science.1185181. doi: 10.1126/science.1185181.
6. Srichaikul T, Nimmannitya S. Hematology in dengue and dengue haemorrhagic fever. Baillieres Best Pract Res Clin Haematol. 2000 Jun;13(2):261-76. doi: 10.1053/beha.2000.0073
7. Kementrian Kesehatan RI. Situasi DBD. Jakarta Selatan: Pusat Data dan Informasi; 2016.
8. Pongpan, S., Wisitwong, A., Tawichasri, C., Patumanond, J., & Namwongprom, S. Development of Dengue Infection Severity Score. ISRN Pediatrics. 2013; 1–6. doi: 10.1155/2013/845876
9. Coffey, L. L., Mertens, E., Brehin, A.-C., Fernandez-Garcia, M. D., Amara, A., Després, P., & Sakuntabhai, A. Human genetic determinants of dengue virus susceptibility. Microbes Infect. 2009;11(2);143–56. doi: 10.1016/j.micinf.2008.12.006
10. Tantracheewathorn, T., Tantracheewathorn, S. Risk Factors of Dengue Shock Syndrome in Children. J Med Assoc Thai. 2007;90(2):272-7.
11. Guzman, MG., Alvarez, M., Halstead, SB. Secondary infection as a risk factor for dengue hemorrhagic fever/dengue shock syndrome: an historical perspective and role of antibody-dependent enhancement of infection. Arch Virol. 2013;158(7):1445-59. doi: 10.1007/s00705-013-1645-3
12. Limkittikul , K., Brett, J., L'Azou, M. Epidemiological Trends of Dengue Disease in Thailand (2000–2011): A Systematic Literature Review. PLoS Negl Trop Dis. 2004;8(11):e3241. doi: 10.1371/journal.pntd.0003241
13. Kamath SR, Ranjit S. Clinical features, complications and atypical manifestations of children with severe forms of dengue hemorrhagic fever in South India. Indian J Pediatr. 2006; 73:889-95.
14. Tantawichien, T. Dengue fever and dengue haemorrhagic fever in adolescents and adults. Paediatr Int Child Health. 32 Suppl 2012;1:22-7. doi: 10.1179/2046904712Z.00000000049.
15. Bethell, DB., Gamble, J., Loc, PP., dkk. Noninvasive Measurement of Microvascular Leakage in Patients with Dengue Hemorrhagic Fever. Clin Infect Dis. 2001;32(2):243-253. doi: 10.1086/318453
16. Hanna-Wakim R, Yasukawa LL, Sung P, dkk. Age-related increase in the frequency of CD4(+) T cells that produce interferon-gamma in response to staphylococcal enterotoxin B during childhood. J Infect Dis. 2009 Dec 15;200(12):1921-7. doi: 10.1086/648375
17. Thanachartwet V, Wattanathum A, sahassananda D., dkk. Dynamic Measurement of Hemodynamic Parameters and Cardiac Preload in Adults with Dengue: A Prospective Observational Study. Plos One. 2016 May 19;11(5):e0156135. doi: 10.1371/journal.pone.0156135.
18. Lovera D, Martinez de Cuellar C, Araya S, dkk. Clinical characteristics of Dengue Shock Syndrome (DSS) in children. Pediatr Infect Dis J. 2016 Dec;35(12):1294-1299. doi: 10.1097/INF.0000000000001308
19. Wali JP, Biswas A, Chandra S, dkk. Cardiac involvement in Dengue Haemorrhagic Fever. Int J Cardiol. 1998;64(1):31–6. [PubMed]
20. Khongphatthanayothin, A., Lertsapcharoen, P., Supachokchaiwattana, P., La-Orkhun, V., Khumtonvong, A., Boonlarptaveechoke, C., Pancharoen, C. Myocardial depression in dengue hemorrhagic fever: Prevalence and clinical description. Pediatr Crit Care Med.2007;8(6):524-9. doi: 10.1097/01.PCC.0000288672.77782.D4
21. Yacoub, S., Wertheim, H., Simmons, CP., Screaton, G., Wills, B. Cardiovascular Manifestations of The Emerging Dengue Pandemic. Nat Rev Cardio. 2014;11: 335-345. doi: 10.1038/nrcardio.2014.40
22. Kabra SK, Juneja R, Madhulika, Jain Y, Singhal T, Dar L, Kothari SS, Broor S. Myocardial dysfunction in children with dengue haemorrhagic fever. Natl Med J India. 1998 Mar-Apr;11(2):59-61.
23. Miranda, CH., Borges, Mde C., Matsuno, AK., Vilar, FC., Gali, LG. Evaluation of Cardiac Involvement During Dengue Viral Infection. Clin Infect Dis.2013;57(6):812-9. doi: 10.1093/cid/cit403.
24. A. Khongphatthallayothin, P. Chotivitayatarakorn, S. Somchit, A. Mitprasart, S. Sakolsattayadorn, C. Thisyakorn. Morbitz type I second degree AV block during recovery from dengue hemorrhagic fever. Southeast Asian J Trop Med Public Health. 2000 Dec;31(4):642-5.
25. Wichmann D, Kularatne S, Ehrhardt S, Wijesinghe S, Brattig NW, Abel W, Burchard GD. Cardiac involvement in dengue virus in dengue virus infections during the 2004/2005 dengue fever season in Sri Lanka. Southeast Asian J Trop Med Public Health. 2009 Jul;40(4):727-30.
26. Dünser, MW., Takala, J., Ulmer, H., dkk. Arterial blood pressure during early sepsis and outcome. Intensive Care Med. 2009;35(7):1225-33. doi: 10.1007/s00134-009-1427-2.
27. Pizarro-Torres D. Dengue With Severe Plasma Leakage: A New Monitoring Approach. Acta Méd Costarric. 2016; 58(3): 115-121.
28. Han J, Ren HQ, Zhao QB, Wu YL, Qiao ZY. Comparison of 3% and 7.5% Hypertonic Saline in Resuscitation After Traumatic Hypovolemic Shock. Shock. 2015 Mar;43(3):244-9. doi: 10.1097/SHK.0000000000000303.
29. Balmaseda, A., Hammond, SN., Pérez, MA., dkk. Short report: assessment of the World Health Organization scheme for classification of dengue severity in Nicaragua. Am J Trop Med Hyg. 2005;73(6):1059-62.
30. Cao, XT., Ngo, TN., Wills, B., dkk. Evaluation of the World Health Organization standard tourniquet test and a modified tourniquet test in the diagnosis of dengue infection in Viet Nam. Trop Med Int Health. 2002;7(2):125-32.
31. Opreanu RC, Arrangoiz R, Stevens P, Morrison CA, Mosher BD, Kepros JP. Hematocrit, systolic blood pressure and heart rate are not accurate predictors for surgery to control hemorrhage in injured patients. Am Surg. 2010 Mar;76(3):296-301.
32. Victorino GP, Battistella FD, Wisner DH. Does tachycardia correlate with hypotension after trauma?. J Am Coll Surg. 2003 May;196(5):679-84. doi: 10.1016/S1072-7515(03)00128-5
Published
2020-08-01
How to Cite
SEIPALLA, Fenska; DHARMAWATI, Ira; WIYASIHATI, Sundari Indah.
Prevalence and Hemodynamic Outcome of Dengue Shock Syndrome in Children Attending the Department of Pediatrics, Dr. Soetomo General Hospital.
Essential: Essence of Scientific Medical Journal, [S.l.], v. 18, n. 1, p. 12-16, aug. 2020.
ISSN 2655-6472.
Available at: <https://ojs.unud.ac.id/index.php/essential/article/view/54049>. Date accessed: 27 apr. 2024.
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Artikel Penelitian
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