Manfaat Lidah Buaya Sebagai Anti Penuaan Melalui Aktivitas Antioksidan
Abstract
Introduction: Elderly population in Indonesia is predicted to increase every year. Aging itself is a process of decreasing physiological integrity that triggers dysfunction and increases the risk of death. One theory of aging is oxidative stress due to free radicals, which can be prevented by increasing antioxidants, including herbs such as aloe vera.
Discussion: Excessive free radicals trigger oxidative stress and cause biomolecular damage to cells. Free radicals are neutralized by antioxidant system which reduces peroxide concentration, affects metabolism, and improves membrane oxidation. Aloe vera contains polysaccharides, specifically mannose-6-phosphate and flavonoids, like kaempeferol, quercertin, and merycerin, which act as antioxidants..
Conclusion: The content of polysaccharides and aloe vera flavonoids acts as an antidote to various free radicals which cause the aging process.
Keywords: Aloe vera, free radical, antioxidant
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References
2. Marta L, Agustinus R, Rizaldy T. Proses Menua, Stres Oksidatif, dan Peran Antioksidan. Kalbemed. 2016; 43(10): 733-736.
3. Pusat Data dan Informasi Kementerian Kesehatan RI. Situasi dan Analisis Lanjut Usia. Jakarta Selatan: Kemenkes RI; 2014.
4. Kesuma S, Rina Y. Antioksidan, Alami dan Sintetik. Padang: Andalas University Press; 2015.
5. Harumi A, Ade Z. Review: Aktivitas Tanaman Lidah Buaya (Aloe vera Linn) sebagai Penyembuh Luka. Farmaka: peer-reviewed. 2016; 15(2): 82-89.
6. Rostita. Sehat, Cantik, dan Penuh Vitalitas Berkat Lidah Buaya. Bandung: PT. Mizan Pustaka; 2008.
7. Schöttker B, Brenner H, Jansen E, Gardiner J, Peasey A, Kubinova R, et al. Evidence for the free radical/oxidative stress theory of ageing from the CHANCES consortium: A meta-analysis of individual participant data. BMC Medicine. 2015; 13:300
8. Geir B, Maryam D, Natalia M, Salvatore C, Bey H, Kateryna S, et al. Brief Challenges on Medical Plants: An Eye-Opening Look at Ageing-Related Disorders. Basic & Clinical Pharmacology & Toxicology. 2018 January 15; 122(1):539-588
9. Erez H, Abraham Z. Antioxidant and Healthy Aging. IMAJ. 2003 May; 5(3): 368-370.
10. Barbara F, Jose A, Miriam M. The Role of Oxidative Stress in the Aging Process. TheScientificWord J. 2010; 10(10): 1121-1128.
11. Nazrah E. Uji Daya Terima Agar-Agar Kombinasi Lidah Buaya (Aloe vera L.) dengan Daun Afrika Selatan (Vernonia amygdalana Delile) [skripsi]. Medan: Universitas Sumatera Utara; 2017.
12. Hery W. Antioksidan Alami dan Radikal Bebas. Yogyakarta: Penerbit Kanisius; 2011.
13. Rosi A, Tantawi D. Antioksidan dalam Dermatologi. JKK. 2017 January;4(1):39-48.
14. Mery R. Upaya Penundaan Proses Penuaan (Degeneratif) Menggunakan Antioksidan dan Terapi Sulih Hormon. J Kes Mas. 2011;5(1):36-40.
15. Soyun C. The Role of Functional Foods in Cutaneous Anti-aging. J of Lifestyle Med. 2014 January 20;4(1):8-16.
16. Marzanna H, Krzysztof D, Danuta G, Anna J, Elzbieta G. Aloe vera (L.) Webb.: Natural Sources of Antioxidants – A Review. Springer: Plant Foods Hum Nutr. 2019 June 18;19(6):1-11.
17. Riyanto, Chatarina W. Stabilitas Sifat Antioksidatif Lidah Buaya (Aloe vera var. chinensis) selama Pengolahan Minuman Lidah Buaya. Agritech. 2012 Februari;32(1):73-78
18. Pankaj K, Deen D, Ritu S, Priyanka P, Sharmistha G, Atul K, et al. Therapeutic and Medicinal Uses of Aloe vera: A Review. Sci Research. 2013;13(4):599-610.
19. Nike R, Mainy S, Bambang C. The Antioxidant Activities, Phenolic Total and Cytotoxicity of Extract and Fractions of Aloe vera Linn. Jurnal Sains dan Matematika. 2015; 23(2):50-54
20. Gaurav K, Prashant S, Daksh B. Evaluation of in vito and in vivo Antioxidant Potential of Polysaccharides from Aloe vera (Aloe barbadensis Miller) gel. Drug Chem Toxicol. 2014;37(2):135-143
21. Anirban R, Dutta G, Sampad G. Evaluation of Anti-oxidative Activity and UV Absorption Potential of The Extract of Aloe vera L. Gel from Different Growth Period of Plants. Elsevier. 2013 June 3;49(13):712-719.
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