EFEKTIVITAS LOW-LEVEL LASER THERAPY DALAM PENYEMBUHAN LUKA SUPERFISIAL PADA PASIEN DEWASA DI ATAS USIA 18 TAHUN
Abstract
Pendahuluan: Luka superfisial sebagai masalah kulit umumnya dianggap sebagai masalah sepele dengan perhatian minimal yang diberikan, terutama karena tidak mengancam jiwa. Namun, ketika tidak diberikan perawatan optimal, luka superifisial dan kesehatan mental dapat menciptakan lingkaran setan yang mengancam kesehatan fisik dan mental. Oleh karena itu, regenerasi dan perbaikan kulit untuk mengoptimalkan penyembuhan adalah topik yang penting untuk didalami.
Pembahasan: Low-level laser therapy (LLLT) telah dianggap sebagai salah satu cara paling efektif dalam perawatan luka superfisial. Artikel ulasan ini menguraikan kesamaan antara pengobatan LLLT dan perbaikan epidermis alami, mekanisme aksi LLLT, dan jenis dan dosis LLLT yang aman yang digunakan sesuai dengan masing-masing jenis laser. Pencarian didasarkan pada studi literatur terbaru yang telah dipublikasikan sebelumnya.
Simpulan: LLLT didefinisikan sebagai pengobatan yang efektif karena pemberian efek lokal tanpa kerusakan pada organ lain. Efektivitas ini terutama disebabkan oleh sifat-sifatnya, yaitu monokromatisitas, koherensi, dan polarisasi yang akan merangsang proliferasi jaringan sel punca. Selain itu, efektivitas LLLT tergantung pada kedua faktor laser dan sifat jaringan yang aplikasi dosis kecil secara teratur akan menghasilkan pengobatan yang lebih optimal daripada jarang digunakan dalam dosis yang lebih besar. Jenis LLLT yang aman dan banyak digunakan adalah Er:YAG, 46-Diode Cluster Probe, HeNe, dan GaAIAs.
Downloads
References
2. Eming SA, Martin P, Tomic-Canic M. Wound repair and regeneration: mechanisms, signaling, and translation. Sci Transl Med 2014;6(265). doi: 10.1126/scitranslmed.3009337.
3. Dekoninck S, Blanpain C. Stem cell dynamics, migration and plasticity during wound healing. Nat Cell Biol 2019;21(1):18–24. doi: 10.1038/s41556-018-0237-6.
4. Ferraq Y, Black DR, Theunis J, Mordon S. Superficial wounding model for epidermal barrier repair studies: Comparison of erbium:YAG laser and the suction blister method. Lasers Surg Med 2012;44(7):525–32. doi: 10.1002/lsm.22054.
5. Ross EV, Childs J. Role of beam spot size in heating targets at depth. Journal of drugs in dermatology 2015;14(12):1437–1442.
6. Kirman CN, Molnar JA. Plastic surgery for laser hair removal: Background, history of the procedure, etiology. Medscape Web site. https://emedicine.medscape.com/article/1271154-overview. Updated March 23, 2023. Accessed March 27, 2023.
7. Cherney K. Laser hair removal side effects and risks. Healthline Web site. https://www.healthline.com/health/beauty-skin-care/laser-hair-removal-side-effects. Updated June 16, 2018. Accessed March 27, 2023.
8. Alberts B, Johnson A, Lewis J, et al. Molecular Biology of the Cell. 4th edition. New York: Garland Science; 2002. General Recombination. Available from: https://www.ncbi.nlm.nih.gov/books/NBK26898/
9. Wallace HA, Basehore BM, Zito PM. Wound Healing Phases. [Updated 2023 Mar 7]. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2023 Jan-. Available from: https://www.ncbi.nlm.nih.gov/books/NBK470443/
10. Wang PH, Huang BS, Horng HC, Yeh CC, Chen YJ. Wound healing. J Chin Med Assoc 2018;81(2):94–101. doi: 10.1016/j.jcma.2017.11.002.
11. Pavletic MM. Basic principles of wound management. Atlas Small Anim Wound Manag Reconstr Surg 2018;33–52. https://doi.org/10.1002/9781119267539.ch3
12. Armstrong DJ, Myer AJ. Basic principles of wound healing. UpToDate Web site. https://www.medilib.ir/uptodate/show/15080. Updated May 19, 2022. Accessed March 27, 2023.
13. Rashidi S, Yadollahpour A, Mirzaiyan M. Low level laser therapy for the treatment of chronic wound: Clinical considerations. Biomed Pharmacol J 2015;8(2):1121–7. doi: 10.13005/bpj/866
14. Rocha AM, Vieira BJ, De Andrade LCF, Aarestrup FM. Effects of low-level laser therapy on the progress of wound healing in humans: the contribution of in vitro and in vivo experimental studies. J Vasc Bras 2007;6(3):257–65. doi: 10.1590/s0100-69912014000200010.
15. Avci P, Gupta A, Sadasivam M, Vecchio D, Pam Z, Pam N, et al. Low-level laser (light) therapy (LLLT) in skin: Stimulating, healing, restoring. Semin Cutan Med Surg 2013;32(1):41.
16. UC San Diego. Laser safety program: Biological effects of laser radiation. UC San Diego Web site. https://blink.ucsd.edu/safety/radiation/lasers/effects.html. Updated October 27, 2020. Accessed March 27, 2023.
17. Samaneh R, Ali Y, Mostafa J, Mahmud NA, Zohre R. Laser therapy for wound healing: A review of current techniques and mechanisms of action. Biosci Biotechnol Res Asia 2015;12:217–23. DOI : http://dx.doi.org/10.13005/bbra/1626
18. Hopkins JT, McLoda TA, Seegmiller JG, Baxter GD. Low-level laser therapy facilitates superficial wound healing in humans: A triple-blind, sham-controlled study. J Athl Train 2004;39(3):223.
19. Posten W, Wrone DA, Dover JS, Arndt KA, Silapunt S, Alam M. Low-level laser therapy for wound healing: mechanism and efficacy. Dermatol Surg 2005;31(3):334–40. doi: 10.1111/j.1524-4725.2005.31086.
20. de Melo VA, dos Anjos DCS, Albuquerque Júnior R, Melo DB, Carvalho FUR. Effect of low level laser on sutured wound healing in rats. Acta Cir Bras 2011;26(2):129–34. https://doi.org/10.1590/S1516-89132014000100008
21. Andrade F do S da SD, Clark RM de O, Ferreira ML. Effects of low-level laser therapy on wound healing. Rev Col Bras Cir 2014;41(2):129–33. doi: 10.1590/s0100-69912014000200010.
22. Hawkins DH, Abrahamse H. The role of laser fluence in cell viability, proliferation, and membrane integrity of wounded human skin fibroblasts following helium-neon laser irradiation. Lasers Surg Med 2006;38(1):74–83. doi: 10.1002/lsm.20271.
23. Pereira AN, De Paula Eduardo C, Matson E, Marques MM. Effect of low-power laser irradiation on cell growth and procollagen synthesis of cultured fibroblasts. Lasers Surg Med 2002;31(4):263–7. doi: 10.1002/lsm.10107.
24. Pourzarandian A, Watanabe H, Aoki A, Ichinose S, Sasaki KM, Nitta H, et al. Histological and TEM examination of early stages of bone healing after Er:YAG laser irradiation. Photomed Laser Surg 2004;22(4):342–50. https://doi.org/10.1089/pho.2004.22.342
SUBMISSION
