RESPONSE OF ANALGESIA, SEDATION, AND RELAXATION OF KETAMINE AND PROPOFOL ANESTHESIA WITH XILASIN PREMEDICATION IN BALI CATTLE

  • Nur Liliana Putri Prihatiningsih Mahasiswa Fakultas Kedokteran Hewan, Fakultas Kedokteran Hewan, Universitas Udayana. Jl. PB. Sudirman, Denpasar, Bali
  • I Gusti Ngurah Sudisma Laboratorium Bedah dan Radiologi Veteriner, Fakultas Kedokteran Hewan, Universitas Udayana. Jl. PB. Sudirman, Denpasar, Bali
  • I Gusti Agung Gde Putra Pemayun Laboratorium Bedah dan Radiologi Veteriner, Fakultas Kedokteran Hewan, Universitas Udayana. Jl. PB. Sudirman, Denpasar, Bali

Abstract

This study aims to determine the response of analgesia, sedation, and relaxation of the use xilasin premedication with anesthesia ketamine, propofol and their combination in bali cattle (Bos sondaicus). Bali cattle are used as many as 12 head which were divided into three treatment groups. This study used a completely randomized design with three treatments which are xilasin combination (0.1 mg) ketamine (2 mg), xilasin combination (0.1 mg) propofol (3 mg), xilasin combination (0.1 mg) ketamine (1 mg) and propofol (1.5 mg). The result of the research showed that ketamine and porofol anesthesia with xilasin premedication in bali cattle had a significant effect (P<0.05) on analgesia, sedation and relaxation responses. The average time for analgesia response is 2.5 – 12.5 minutes with analgesia duration of 5-17.5 minutes. For sedation response the average time of occurrence is 2.5-13.7 minutes with sedation duration of 5-13.75 minutes. The response time fot the occurrence of 5-12.5 minutes of relaxation with relaxation duration 2.5-23.75 minutes. In this study it can be concluded that the xilasin-ketamine-propofol combination is better fo bali cattle anesthesia becauses it produces a faster induction with a longer duration.

Downloads

Download data is not yet available.

References

Adams RH. 2001. Veterinary Pharmacology and Therapeutics. 8th Ed. IOWA State University Press Ames.
Arai S, Yoshioka K, Suzuki C, Takahashi H, Itoh T, Nakano S. 2006. Development of a neurosurgical operating table for adult cattle and changes in intracranial pressure and blood pressure in adult cattleungergoing long-time isoflurance anesthesia. J. Vet. Med. Sci. 68(4): 337-343.
Dzikti TB, Chanaiwa S, Mponda O, Sigauke C, Dzikti LN. 2007. Comparison of quality of induction of anesthesia between intramusculary administered ketamin, intravenously administerd ketamin and intravenously administered propofol in xylazine premediated cats. J. South African Vet. Assoc. 78: 201-204.
Flecknell P. 2009. Laboratory animal anaesthesia. Third Edition. Newcastle-upon-Tye, UK.
Franks NP. 2008. General anesthesia: from molecular targets to neuronal athways of sleep and arousal. Nat. Rev. Neurosci. (9): 379-386.
Hakim A, Suryadi, Susilawati T, Nurgiartiningsih A. 2008. Pengembangan sistem manajemen breeding sapi bali. Sains Peternakan. 6(1): 9-17.
Henscel O, Keith E, Dipson, Bordey A, 2008. GABAA receptors, anesthetics and anticonvullsants in brain development. CNS Neurol. Disorders Drug Targets. 7: 211-224.
Gorda IW, Wardhita AAGJ. 2010. Perbandingan waktu induksi, durasi, dan pemulihan anestesi dengan penambahan premedikasi atropine-xylazin dan atropine-diazepam untuk anestesi umum ketamine pada burung merpati (Columba Livia). Bul. Vet. Udayana. 2(2): 93-100.
Katzung B. 2002. Farmakologi Dasar dan Klinik. Jakrta: Bagian Farmakologi Kedokteran Universitas Airlangga.
Kelly E, Ryan E. 2018. Bovine caesareans: alternative approaches to difficult cases. Vet. Ireland J. 10(8): 600-608.
Lee L. 2006. Anesthetic Monitoring. Veterinary Surgry, Veterinary Health Sciences. Oklahoma State University, Amerika Serikat.
McKelvey D, Hollingshead KW. 2003. Veterinary Anesthesia and Analgesia. 3thEd. United States of America: Mosby. Pp. 448.
Muchhalambe B, Dilipkumar D, Shivaprakash BV, Venkatgiri, Manjunath P. 2018. Clinical and phycological evaluation of midozolam- propofol and xylazine-propofol induction combination for isoflurane anathesia in cattle. Pharm. Innov. J. 7(8): 08-11.
Oka IGL. 2010. Conservation and genetic improvement of bali cattle. Proc. Conservation and Improvement of World Indigenous Cattle. Pp. 110-117.
Purwantara B, Noor RR, Andersson G, Rodriguez-Martinez H. 2012. Banteng and bali cattle in Indonesia: status and forecasts. Reprod. Dom. Anim. 47(Suppl. 1): 2-6.
Spandola F, Costa G, Interland C, Musico M. 2019. Hyaluronidase, with xylazine and ketamine reducing immobilization time in wild cattle (Bos taurus). Large Anim. Rev. 25: 159-161.
Sudisma IGN, Pemayun IGAGP, Warditha AAGJ, Gorda IW. 2016. Ilmu Bedah Veteriner dan Teknik Operasi. Swasta Nulus, Denpasar. Pp. 117-132.
Stawicki SP. 2007. Common sedative agents. OPUS 12Scientist 1: 8-9.
Yudaniayanti I, Yusuf D, Setyono H, Arifin M, Tehupuring B, Tjitro H. 2012. Profil tekanan intra okuler penggunaan kombinasi ketamin-xilasin dan ketamin-midazolam pada kelinci. Vet. Med. J. 1(1): 33-38.
Published
2022-01-29
How to Cite
PRIHATININGSIH, Nur Liliana Putri; SUDISMA, I Gusti Ngurah; PEMAYUN, I Gusti Agung Gde Putra. RESPONSE OF ANALGESIA, SEDATION, AND RELAXATION OF KETAMINE AND PROPOFOL ANESTHESIA WITH XILASIN PREMEDICATION IN BALI CATTLE. Buletin Veteriner Udayana, [S.l.], p. 511-516, jan. 2022. ISSN 2477-2712. Available at: <https://ojs.unud.ac.id/index.php/buletinvet/article/view/58968>. Date accessed: 21 nov. 2024. doi: https://doi.org/10.24843/bulvet.2022.v14.i05.p10.
Section
Articles