ACTIVITY OF ALANIN AMINOTRANSFERASE AND ASPARTAT AMINOTRANSFERASE IN BROILER WITH ADDITION OF TEMULAWAK FLOUR IN FEED

  • Putu Diah Puspa Adhi Faculty of Veterinary Medicine Udayana University
  • Ida Bagus Komang Ardana Laboratory of Veterinary Clinical Pathology, Faculty of Veterinary Medicine Udayana University
  • Anak Agung Sagung Kendran Laboratory of Veterinary Clinical Pathology, Faculty of Veterinary Medicine Udayana University

Abstract

Curcuma (Curcuma xanthorrhiza Roxb.) is one of the medicinal plants, which is widely used by the community, including used a lot in animals because it has many benefits for health. The purpose of this study is to find out the effect of the addition of curcuma flour on the feed toward the activity of ALT and AST on the broiler. This study used a Completely Randomized Design (CRD) with 24 female broilers aged 14 days which were divided into four groups, namely group P0 (normal feed without addition of curcuma flour), P1 group (curcuma flour 10gr/kg of the feed)), P2 (curcuma flour 20gr/kg of the feed)), and P3 (curcuma flour 30gr/kg of the feed)). After 35 days, the blood is taken through the brachial vein using 5ml syringe. Then, the examination of ALT and AST activity is conducted by using Photometer 5010. The data were analyzed by using ANOVA. The results showed that the addition of curcuma flour in broiler's feed did not affect the activity of ALT and AST (P>0.05). From the study, it can be concluded that the addition of curcuma flour in broiler's feed the dose 10 gr/kg of feed until 30 gr/kg of feed for 21 days were still classified as safe dosage.

Downloads

Download data is not yet available.

References

Amalia Z, Adisasmito W. 2017. Analysis of policy making factors on the prohibition of hormones and antibiotics use for feed as a public health protection. J. Indonesian Health Policy and Administration. 2(2): 14-19.
BPOM RI (Badan Pengawas Obat dan Makanan Republik Indonesia). 2005. Gerakan Nasional Minum Temulawak. Info POM. 6(6): 1-12.
Candra AA. 2013. Aktivitas hepatoprotektor temulawak pada ayam yang diinduksi pemberian parasetamol. J Penelitian Pertanian Terapan. 13(2): 137-143.
Darmawan A, Putra FD, Isroli I, Sugiharto. 2016. Bobot hati, kadar SGOT dan SGPT pada ayam broiler yang diberi ransum menggunakan onggok terfermentasi acremonium chorticola dan/atau antibiotik. Seminar Nasional Program Studi Peternakan UNS.
Devaraj S, Ismail S, Ramanathan S, Marimuthu S, Mun Fei Y. 2010. Evaluation of the hepatoprotective activity of standardized ethanolic extract of curcuma xanthorrhiza roxb. J. Med. Plants Res. 4(23): 2512-2517.
Dian LMB, Sarayar CLK, Marie N, Utiah W. 2014. Efektivitas penambahan tepung temulawak dan tepung temu putih dalam ransum komersial terhadap performans ayam pedaging. J. Zootek. 34: 85-94.
Giannini EG, Testa R, Savarino V. 2005. Liver enzyme alterations: A guide forclinicians. Canadian Med. Asso. J. 172(3): 1497-1503.
Hadi S. 2000. Hepatologi. Bandung: Mandar Maju.
Irfan IZ, Esfandiari A. 2016. Aktivitas aspartate aminotransferase dan gamma glutamyltransferase pada sapi pejantan unggul. J. Ilmu Ternak. 16(1): 11-17.
Jupakan KVF, Kennedy PC, Peter C. 1993. Pathology of domestic animal. London: Academic Press. Pp. 325-346.
Martani HR, Murwani R. 2005. Aktivitas serum glutamat oksaloasetat transaminase dan serum glutamat piruvat transaminase broiler yang diberi ekstrak mengkudu (Morinda citrifolia) sebagai alternatif aditif klortetrasiklin. Proc. Seminar Nasional Fakultas Peternakan UGM Yogyakarta.
Nirmala AZ. 2013. Perbedaan efek hepatoprotektif ekstrak etanolik kunyit, temulawak, dan kombinasinya pada mencit balb/c yang diinduksi parasetamol. Skripsi. Fakultas Kedokteran Universitas Sebelas Maret. Surakarta.
Rahardjo M. 2010. Penerapan SOP budidaya untuk mendukung temulawak sebagai bahan baku obat potensial. Perspektif. 9(2): 78-93.
Salam S, Sunarti D, Isroli. 2014. Pengaruh suplementasi jintan hitam (Nigella sativa) giling terhadap AST, ALT, dan berat organ hati broiler. J. Peternakan Indonesia. 16(1): 40-45.
Samarasinghe K, Wenk C, Silva KFST, Gunasekera JMDM. 2003. Turmeric root powder and manano ligo sacharides as alternative to antibiotic in broiler chicken diets. Asian-Aust. J. Anim. Sci. 16: 1495-1500.
Sampurn IP, Nindhia TS. 2008 Analisis data dengan SPSS dalam rancangan percobaan. Cetakan Pertama. Udayana University Press. Bali
Sukardi, Saptariyanti AKP, Taryana A. 2010. Analisis kelayakan industri tablet effervescent dari ekstrak temulawak (Curcuma xanthorrhiza Roxb.). J. Teknologi Pertanian. 10(8): 162-178.
Tampubolon SR, Ardana IBK, Sudira IW. 2014. Aktivitas alanine aminotransferase dan aspartat aminotransferase pada mencit yang diberikan jamu temulawak. Indonesia Medicus Veterinus. 3(3): 200-205.
Published
2020-02-28
How to Cite
PUSPA ADHI, Putu Diah; ARDANA, Ida Bagus Komang; KENDRAN, Anak Agung Sagung. ACTIVITY OF ALANIN AMINOTRANSFERASE AND ASPARTAT AMINOTRANSFERASE IN BROILER WITH ADDITION OF TEMULAWAK FLOUR IN FEED. Buletin Veteriner Udayana, [S.l.], p. 45-49, feb. 2020. ISSN 2477-2712. Available at: <https://ojs.unud.ac.id/index.php/buletinvet/article/view/42663>. Date accessed: 12 july 2020. doi: https://doi.org/10.24843/bulvet.2020.v12.i01.p08.
Section
Articles