A Studi Histologi Kolon Ayam Broiler dengan Pemberian Suplemen Asam Butirat
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https://doi.org/10.24843/bulvet.2019.v11.i02.p09
Abstrak
Tujuan penelitian untuk mengetahui pengaruh perbedaan dosis dan lama pemberian suplemen asam butirat terhadap ketebalan lapisan kolon ayam broiler. 24 ekor ayam broiler dirancang dalam penelitian pola faktorial 3x4 yaitu 3 faktor dosis suplemen (0; 0,5; dan 1 g suplemen/kg pakan) dan faktor lama pemberian (1,2,3, dan 4 minggu). Ayam dibagi atas tiga kelompok yaitu kelompok kontrol (P1), kelompok dengan pemberian suplemen asam butirat 0,5 (P2), dan 1 g suplemen/kg pakan (P3). Setiap minggu, ayam broiler sebanyak dua ekor dari masing-masing kelompok dinekropsi dan diambil bagian kolonnya untuk dibuat preparat histologi menggunakan pewarnaan HE. Perubahan yang diamati meliputi ketebalan lapisan mukosa, submukosa, muskularis, dan serosa menggunakan aplikasi ZEN. Data dianalisis dengan sidik ragam dan dilanjutkan uji Duncan jika ada perbedaan yang nyata. Hasil pengukuran menunjukkan perbedaan dosis asam butirat tidak berpengaruh terhadap ketebalan lapisan kolon tetapi berpengaruh terhadap perubahan histologis kolon. Lama pemberian asam butirat berpengaruh terhadap ketebalan tunika mukosa, submukosa, muskularis, dan serosa
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Referensi
Adil S, Tufail B, Gulam AB, Masood S, Manzoor R. 2010. Effect of dietary supplementation of organic acids on performance, intestinal histomorphology, and serum biochemistry of broiler chicken. Vet. Med. Int. 2010(479485): 1–7.
Bacha WJ, Bacha LM. 2012. Color atlas of veterinary histology. 3rd Ed. UK, John Wiley & Sons, Ltd.
Banks J. 1981. Applied veterinary histology. London, Williams and Wilkins Baltmore. Pp: 102.
Baum B, Meneses F, Kleinschmidt S, Nolte I, Trautwein MH. 2007. Age-related histomorphologic changes in the canine gastrointestinal tract: A histologic and imunohistologic study. World J. Gastroenterol. 13(1): 152-157.
Canani RB, Costanzo MD, Leone L, Pedata M, Meli R, Calignano A. 2011. Potential beneficial effects of butyrate in intestinal and extraintestinal diseases. World J. Gastroenterol. 17(12): 1519-1528.
Cassidy MM, Fitzpatrick LR, Vahouny GV. 1984. The effect of fiber in the postweaning diet on nutritional and intestinal morphological indices in the rats. 2nd Washington Symp. Dietary Fiber.
Comalada M, Bailon E, Villoslada ODHFL, Xaus J, Zarzuelo A, Galvez J. 2006. The effects of short-chain fatty acids on colon epithelial proliferation and survival depend on the cellular phenotype. J. Cancer Res. Clin. Oncol. 132: 487-497.
Dehkordi RF, Ghahremani P. 2015. Developmental study of rectum in broiler chicken: A stereological and morphometrical study. Vet. Res. Forum. 7(1): 41-45.
Fernandes BCS, Martins MRFB, Mendes AA, Milbradt EL, Sanfelice C, Martins BB, Aguiar EF, Bresne C. 2014. Intestinal integrity and performance of broiler chickens fed a probiotic, a prebiotic, pr an organic acid. Braz. J. Poult. Sci. 16(4): 417-424.
Fernandes T, Oliveira MI, Castro R, Araujo B, Viamonte B, Cunha R. 2014. Bowell wall thickening at CT: simplifying the diagnosis. Insights Imaging. 5: 195-208.
Ganong WF. 1995. Fisiolofi kedokteran. Edisi 14. Jakarta, Penerbit Buku Kedokteran EGC.
Hamedi S, Shomali T, Akbarzadeh A. 2013. Prepubertal and pubertal caecal wall histology in Japanese quails (Coturnix coturnix japonica). Bulgarian J. Vet. Med. 16(2): 96- 101.
Hamer HM, Jonkers D, Venema K, Sanvhoutvin S, Troost FJ, Brummer RJ. 2008. Review Article: the role of butyrate on colonic function. Aliment. Pharmacol. Ther. 27: 104–119.
Karaki S, Kuwahara A. 2010. Roles of Short-Chain Fatty Acids and their Receptor in Colonic Motility. Biosci. Microflora. 29(1): 31-40.
Khan SH, Iqbal J. 2016. Recent advances in the role of organic acids in poultry nutrition. J. Appl. Anim. Res. 44(1): 359-369.
Liu W, Yang Y, Zhang J, Gatlin DM, Ringo E, Zhou Z. 2014. Effect of dietary microencapsulated sodium butyrate on growth, intestinal mucosal morphology, immune response and adhesive bacteria in juvenile common carp (Cyprinus carpio) pre-fed with or without oxidised oil. British J. Nutr. (112): 15–29.
Murdiati TB. 1997. Pemakaian antibiotika dalam usaha peternakan. Wartazoa. 6(1): 18-20.
Ochiai K, Ochiai TK. 2006. Effect of butyric acid on the periodontal tissue. Jap. Dental Sci. Rev. 45: 75-82.
Putra IGNY, Sudarma M, Djelantik AAAW. 2015. Faktor-faktor yang mempengaruhi masyarakat membeli daging ayam boiler di Kabupaten Bangli. E-J. Agrib. Agrowisata. 4 (1): 47-55.
Teirlynck E, Bjerrum L, Eeckhaut V, Huygebaert G, Pasmans F, Haesebrouck F, Dewulf J, Ducatelle R, Van Immersel F. 2009. The cereal type in feed influences gut wall morphology and intestinal immune cell infiltration in broiler chickens. British J. Nutr. 102: 1453-1461.
Uni Z, Noy Y, Sklan D. 1996. Developmental parameters of th small intestines in heavy and light strain chicks pre and post-hatch. British Poult. Sci. 36: 63-71.
Van Immerseel F, Boy ENF, Gantois I, Timbermont L, Bohez L, Pasmans F, Haesebrouck F, Ducatelle R. 2005. Supplementation of coated butyric acid in the feed reduces colonization and shedding of Salmonella in poultry. Poult. Sci. 84: 1851-1856.
Woong KJ, Hyuk KJ, Yong KD. 2015. Dietary organic acids for broiler chickens: a review. Rev. Colomb. Cienc. Pecuar. 28(2): 109-123.
Zaleski A, Banaszkiewicz A, Walkowiak J. 2013. Butyric acid in irritable bowel syndrome. Prz. Gastroenterol. 8(6): 350–353.
Zavarize KC, Sartori JR, Gonzales E, Pezzato AC. 2012. Morphological changes of the intestinal mucosa of broilers and layers as affected by fasting before sample collection. Braz. J. Poult. Sci. 14(1): 21-25.
Bacha WJ, Bacha LM. 2012. Color atlas of veterinary histology. 3rd Ed. UK, John Wiley & Sons, Ltd.
Banks J. 1981. Applied veterinary histology. London, Williams and Wilkins Baltmore. Pp: 102.
Baum B, Meneses F, Kleinschmidt S, Nolte I, Trautwein MH. 2007. Age-related histomorphologic changes in the canine gastrointestinal tract: A histologic and imunohistologic study. World J. Gastroenterol. 13(1): 152-157.
Canani RB, Costanzo MD, Leone L, Pedata M, Meli R, Calignano A. 2011. Potential beneficial effects of butyrate in intestinal and extraintestinal diseases. World J. Gastroenterol. 17(12): 1519-1528.
Cassidy MM, Fitzpatrick LR, Vahouny GV. 1984. The effect of fiber in the postweaning diet on nutritional and intestinal morphological indices in the rats. 2nd Washington Symp. Dietary Fiber.
Comalada M, Bailon E, Villoslada ODHFL, Xaus J, Zarzuelo A, Galvez J. 2006. The effects of short-chain fatty acids on colon epithelial proliferation and survival depend on the cellular phenotype. J. Cancer Res. Clin. Oncol. 132: 487-497.
Dehkordi RF, Ghahremani P. 2015. Developmental study of rectum in broiler chicken: A stereological and morphometrical study. Vet. Res. Forum. 7(1): 41-45.
Fernandes BCS, Martins MRFB, Mendes AA, Milbradt EL, Sanfelice C, Martins BB, Aguiar EF, Bresne C. 2014. Intestinal integrity and performance of broiler chickens fed a probiotic, a prebiotic, pr an organic acid. Braz. J. Poult. Sci. 16(4): 417-424.
Fernandes T, Oliveira MI, Castro R, Araujo B, Viamonte B, Cunha R. 2014. Bowell wall thickening at CT: simplifying the diagnosis. Insights Imaging. 5: 195-208.
Ganong WF. 1995. Fisiolofi kedokteran. Edisi 14. Jakarta, Penerbit Buku Kedokteran EGC.
Hamedi S, Shomali T, Akbarzadeh A. 2013. Prepubertal and pubertal caecal wall histology in Japanese quails (Coturnix coturnix japonica). Bulgarian J. Vet. Med. 16(2): 96- 101.
Hamer HM, Jonkers D, Venema K, Sanvhoutvin S, Troost FJ, Brummer RJ. 2008. Review Article: the role of butyrate on colonic function. Aliment. Pharmacol. Ther. 27: 104–119.
Karaki S, Kuwahara A. 2010. Roles of Short-Chain Fatty Acids and their Receptor in Colonic Motility. Biosci. Microflora. 29(1): 31-40.
Khan SH, Iqbal J. 2016. Recent advances in the role of organic acids in poultry nutrition. J. Appl. Anim. Res. 44(1): 359-369.
Liu W, Yang Y, Zhang J, Gatlin DM, Ringo E, Zhou Z. 2014. Effect of dietary microencapsulated sodium butyrate on growth, intestinal mucosal morphology, immune response and adhesive bacteria in juvenile common carp (Cyprinus carpio) pre-fed with or without oxidised oil. British J. Nutr. (112): 15–29.
Murdiati TB. 1997. Pemakaian antibiotika dalam usaha peternakan. Wartazoa. 6(1): 18-20.
Ochiai K, Ochiai TK. 2006. Effect of butyric acid on the periodontal tissue. Jap. Dental Sci. Rev. 45: 75-82.
Putra IGNY, Sudarma M, Djelantik AAAW. 2015. Faktor-faktor yang mempengaruhi masyarakat membeli daging ayam boiler di Kabupaten Bangli. E-J. Agrib. Agrowisata. 4 (1): 47-55.
Teirlynck E, Bjerrum L, Eeckhaut V, Huygebaert G, Pasmans F, Haesebrouck F, Dewulf J, Ducatelle R, Van Immersel F. 2009. The cereal type in feed influences gut wall morphology and intestinal immune cell infiltration in broiler chickens. British J. Nutr. 102: 1453-1461.
Uni Z, Noy Y, Sklan D. 1996. Developmental parameters of th small intestines in heavy and light strain chicks pre and post-hatch. British Poult. Sci. 36: 63-71.
Van Immerseel F, Boy ENF, Gantois I, Timbermont L, Bohez L, Pasmans F, Haesebrouck F, Ducatelle R. 2005. Supplementation of coated butyric acid in the feed reduces colonization and shedding of Salmonella in poultry. Poult. Sci. 84: 1851-1856.
Woong KJ, Hyuk KJ, Yong KD. 2015. Dietary organic acids for broiler chickens: a review. Rev. Colomb. Cienc. Pecuar. 28(2): 109-123.
Zaleski A, Banaszkiewicz A, Walkowiak J. 2013. Butyric acid in irritable bowel syndrome. Prz. Gastroenterol. 8(6): 350–353.
Zavarize KC, Sartori JR, Gonzales E, Pezzato AC. 2012. Morphological changes of the intestinal mucosa of broilers and layers as affected by fasting before sample collection. Braz. J. Poult. Sci. 14(1): 21-25.
Diterbitkan
2019-08-31
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HIDAYATI, Zumara Mufida; BERATA, I Ketut; SETIASIH, Ni Luh Eka.
A Studi Histologi Kolon Ayam Broiler dengan Pemberian Suplemen Asam Butirat.
Buletin Veteriner Udayana, [S.l.], p. 166-175, aug. 2019.
ISSN 2477-2712.
Tersedia pada: <https://ojs.unud.ac.id/index.php/buletinvet/article/view/41965>. Tanggal Akses: 20 feb. 2026
doi: https://doi.org/10.24843/bulvet.2019.v11.i02.p09.
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