ELEVATION OF SERUM C-REACTIVE PROTEIN AS A PREDICTOR FOR SYSTEMIC INFLAMMATORY RESPONSE SYNDROME IN CERVICAL SPINAL CORD INJURY PATIENTS

  • Stanley-Ketting Oliver Department of Surgery, Faculty of Medicine Udayana University/ Sanglah General Hospital, Bali-Indonesia
  • T. G. B. Mahadewa Department of Neurosurgery, Faculty of Medicine Udayana University/ Sanglah General Hospital, Bali-Indonesia
  • and S. Maliawan Department of Neurosurgery, Faculty of Medicine Udayana University/ Sanglah General Hospital, Bali-Indonesia

Abstract

Objectives: Spinal cord injury has been an important medical issue with high incidence, complications, and mortality rate. For the past 2 decades, there have been a number of researches about the role of inflammatory mediators in trauma patients. However, up to now, there were limited references about the role of CRP as a predictor of SIRS in cervical spinal cord injury. Methods: This was an analytical prospective cohort study of 28 patients to determine the role of increase CRP serum as a predictor for SIRS in cervical spinal cord injury in Sanglah General Hospital, Bali-Indonesia. The data were descriptively analyzed by applying univariate and multivariate analysis to determine the role of increase CRP serum with SIRS in cervical spinal cord injury. Results were considered significant if p < 0.05. Results: From 28 samples collected, 18 samples (64.28%) were male, 12 samples were in >50 years old age group (42,86%), and the most frequent spinal cord injury scale was ASIA A (12 samples, 42,86%). Both univariate and multivariate analysis showed that increased serum CRP and ASIA Score were significant predictors of SIRS in cervical spinal cord injury patients. Conclusion: Increase in serum CRP value can be used as a reliable predictor for SIRS in cervical spinal cord injury patients.

Author Biographies

Stanley-Ketting Oliver, Department of Surgery, Faculty of Medicine Udayana University/ Sanglah General Hospital, Bali-Indonesia

Department of Surgery, Faculty of Medicine Udayana University/

Sanglah General Hospital, Bali-Indonesia

T. G. B. Mahadewa, Department of Neurosurgery, Faculty of Medicine Udayana University/ Sanglah General Hospital, Bali-Indonesia

Department of Neurosurgery, Faculty of Medicine Udayana University/

Sanglah General Hospital, Bali-Indonesia

and S. Maliawan, Department of Neurosurgery, Faculty of Medicine Udayana University/ Sanglah General Hospital, Bali-Indonesia

Department of Neurosurgery, Faculty of Medicine Udayana University/

Sanglah General Hospital, Bali-Indonesia

Published
2013-08-03
How to Cite
OLIVER, Stanley-Ketting; MAHADEWA, T. G. B.; MALIAWAN, and S.. ELEVATION OF SERUM C-REACTIVE PROTEIN AS A PREDICTOR FOR SYSTEMIC INFLAMMATORY RESPONSE SYNDROME IN CERVICAL SPINAL CORD INJURY PATIENTS. BALI MEDICAL JOURNAL, [S.l.], aug. 2013. ISSN 2302-2914. Available at: <https://ojs.unud.ac.id/index.php/bmj/article/view/6269>. Date accessed: 21 may 2019.

Keywords

C-Reactive Protein, Systemic Inflammatory Response Syndrome, Cervical Spinal Cord Injury.