Histomorphometric of duodenum in male rabbits after fed commercial feed supplemented by cod liver oil
Abstract
Fish oil is a source of long-chain polyunsaturated fatty acids (LCPUFA) that can be used as supplementary feed in commercial feed to increase male rabbit productivity. PUFAs function in various physiological processes, including in the digestive system.This study aimed to determine the histomorphometrics of male rabbits duodenum after fed commercial feed supplemented by cod liver oil. The experimental design used was a Completely Randomized Design (CRD) with four feed packages, namely commercial feed without cod liver oil (P0) as a control, commercial feed supplemented with cod liver oil 3% (P1), 4.5% (P2) and 6% (P3). Each consists of five male local rabbits as replicates and given starting female rabbits 1-3 months. The parameters observed were villi height, villi width, crypt depth, and tunica mucosa thickness of the duodenum in male rabbits. The data obtained were analyzed with Anova and if significantly different were further tested with DMRT. The results showed that cod liver oil supplementation in commercial feed was significantly different (p<0.05) to the histomorphometric parameters (villi height, villi width, crypt depth, and thickness of the tunica mucosa) of the duodenum in male rabbits. Can be concluted that supplementation of cod liver oil in commercial feed can increase the histomorphometrics of male local rabbits duodenum.
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References
Alturkistani HA, Tashkandi FM, Mohammedsaleh ZM. 2016. Histological stains:a literature review and case study. Glob. J. Health Sci., 8(3):72–79
Auger C, Said A, Nguyen PN, Chabert P, Idris-khodja N, Schini-kerth VB. 2016. Potential of food and natural products to promote endothelial and vascular health. J. Cardiovasc. Pharmacol., 68:11–18
Bazinet RP, Laye S. 2014. Polyunsaturated fatty acids and their metabolites in brain function and disease. Nat. Rev. Neurosci., 15:771-785
Choct M. 2009. Managing gut health through nutrition. Br. Poult. Sci., 50:9-15
de Oliveira MC, da Silva DM, Dias DMB. 2013. Effect of feed restriction on organs and intestinal mucosa of growing rabbits. R. Bras. Zootec., 42(7):530-534
El-Gogary MR, El-Moghazy MM, El-Atrsh A, Tousson E. 2014. Effect of fish oil administration on growth performance, some blood parameters, duodenum and caecum histology of growing rabbits. Egypt. J. Basic Appl. Phsiol., 13:45-56
Elnasharty MAI, Abou-Ghanema, Sayed-Ahmed A, Elnour AA. 2013. Mucosal- submucosal changes in rabbit duodenum during development. World Academy of Science, Engineering and Technology, 76:500-508
Ermayanti NGAM, Oka IGL, Mahardika IG, Suyadnya IP. 2018. Profil lipid kelinci (Lepus sp.) jantan lokal yang diberi pakan komersial disuplementasi minyak hati ikan kod. Jurnal Biologi Udayana, 22(1):7-12
Ezema C, Eze C. 2012. Determination of The effect of probiotic (Saccharomyces cerevisiae) on growth performance and hematological parameters of rabbits. Comaparative Clinical Pathology, 21:73-76
Fenton JI, Hord NG, Ghosh S. 2013. Immunomodulation by dietary long chain omega-3 fatty acids and the potential for adverse health outcomes. Prostaglandins Leukot Essent Fatty Acids, 89:379-390
Gholami H, Chamani M, Towhidi A, Fazeli MH. 2011. Improvement of semen quality in holstein bulls during heat stress by dietary supplementation of omega-3 fatty acids. Int. J. Fertil. Steril., 4(4):160-167
Gurr MI, Harwood JL, Frayn KN, Murphy DJ, Michell RH. 2016. Lipids: Biochemistry, Biotechnology and Health, 6th ed., Wiley/Blackwell: Oxford, UK
Hidayat SCM, Harimurti S, Yusiati LM. 2016. Pengaruh suplementasi probiotik bakteri asam laktat terhadap histomorfologi usus dan performan puyuh jantan. Buletin Peternakan. 40 (2): 101-106
Ilsley SE, Miller HM, Kamel C. 2005. Effects of dietary quillaja saponin and curcumin on the performance and immune status of weaned piglets. J. Anim. Sci., 83:82-88
Kalish BT, Fallon EM, Puder M. 2012. A tutorial on fatty acid biology. JPEN J. Parenter Enteral Nutr., 36:380-388
Konieczka P, Barszcz M, Choct M, Smulikowska S. 2018. The interactive effect of dietary n-6:n-3 fatty acid ratio and vitamin E level on tissue lipid peroxidation, DNA damage in intestinal epithelial cells, and gut morphology in chickens of different ages. Poult. Sci., 97(1):149-158
Kowalska D, Bielanski P. 2007. Effect of Dietary fish oil supplement on rearing performance of young rabbits and quality of their meat. Pol. J. Food Nutr. Sci., 57(3):63-66
Lisnahan CV, Wihandoyo, Zuprizal, Harimurti S. 2019. Morfologi usus ayam kampung umur 20 minggu yang disuplementasi dl-metionin dan l-lisin HCL dalam pakan. Journal of Tropical Animal Science and Technology, 1(1):14-21
Luchtman DW, Song C. 2013. Cognitive enhancement by omega-3 fatty acids from child-hood to old age: findings from animal and clinical studies. Neuropharmacology. 64:550-565
Majid NC, Simanjuntak P, Suwarno T. 2019. Uji aktivitas anti hiperlipidemia minyak ikan gindara (Lepidocybium flavobrunneum) pada tikus putih jantan dewasa galur wistar. Jurnal Ilmu Kesehatan, 18(3):77-81
Menni C, Zierer J, Pallister T, Jackson MA, Long T, Mohney RP, Steves CJ, Spector TD, Valdes AM. 2017. Omega-3 fatty acids correlate with gut microbiome diversity and production of N-carbamylglutamate in middle aged and elderly women. Sci. Rep., 7:11079
Maertens L, Aerts JM, De Brabander DL. 2005. Effect of a diet rich in n-3 fatty acids on the performances and milk composition of does and the viability of their progeny. In Proc.: 11ème J. Rech. Cunicoles, Bolet G. (Ed.) ITAVI, publ., Paris, France, 29&30:205-208
Pilevar M, Arshami JAAD, Golian A, Basami MR. 2011. Effects of dietary n-6: n-3 ratio on immune and reproductive systems of pullet chicks. Poult. Sci, 90:1758-1766
Raatz SK, Redmon JB, Wimmergren N, Donadio JV, Bibus DM. 2009. Enhanced absorption of omega-3 fatty acids from emulsified compared with encapsulated fish oil. J. Am. Diet Assoc., 109:1076-1081
Rajput N, Muhammad N, Yan R, Zhong X, Wang T. 2013. Effect of dietary supplementation of curcumin on growth performance, intestinal morphology and nutrients utilization broiler chicks. J. Japan Poult Sci. Assoc., 50:44-52
Ristic-Medic D, Vucic V, Takic M, Karadzic I, Glibetic M. 2013. Polyunsaturated fatty acids in health and disease. J. Serb. Chem. Soc., 78(9):1269-1289
Samuelsson B. 2012. Role of basic science in the development of new medicines: examples from the eicosanoid field. J. Biol. Chem., 287:10070-10080
Sherwood L, Klandorf H, Yancey P. 2013. Animal Physiology: From Genes to Organism. 2rd ed. Publisher by Brooks Cole, Cengange Learning
Spector A, Kim H-Y. 2015. Discovery of essential fatty acids. J. Lipid Res., 56:11–21
Turner D, Shah PS, Steinhart AH. 2011. Maintenance of remis-sion in inflammatory bowel disease using omega-3 fatty acids (fish oil): a systematic review and meta-analyses. Inflamm Bowel Dis.,17:336-345
Vangaveti VN, Jansen H, Kennedy RL, Malabu UH. 2016. Hydroxyoctadecadienoic acids: oxidised derivatives of linoleic acid and their role in inflammation associated with metabolic syndrome and cancer. Eur. J. Pharmacol., 785:70-76
Wei Z, Wang W, Chen J, Yang D, Yan R, Cai Q. 2014. A prospective, randomized, controlled study of omega-3 fish oil fat emulsion-based parenteral nutrition for patients following surgical resection of gastric tumors. Nutrition Journal, 13:25-36
Yu H-N, Zhu J, Pan W-S, Shen S-R, Shan W-G, Das UN. 2014. Effects of fish oil with a high content of n-3 polyunsaturated fatty acids on mouse gut microbiota. Archives of Medical Research, 45(Issue 3):195-200
Zarate R, El Jaber-Vazdekis N, Tejera N, Perez JA, Rodriguez C. 2017. Significance of long chain polyunsaturated fatty acids in human health. Clin Transl Med., 6(1):25
Zeitz JO, Fennhoff J, Kluge H, Stangl GI, Eder K. 2015. Effects of dietary fats rich in lauric and myristic acid on performance, intestinal morphology, gut microbes, and meat quality in broilers. Poult. Sci., 94:2404-2413
Auger C, Said A, Nguyen PN, Chabert P, Idris-khodja N, Schini-kerth VB. 2016. Potential of food and natural products to promote endothelial and vascular health. J. Cardiovasc. Pharmacol., 68:11–18
Bazinet RP, Laye S. 2014. Polyunsaturated fatty acids and their metabolites in brain function and disease. Nat. Rev. Neurosci., 15:771-785
Choct M. 2009. Managing gut health through nutrition. Br. Poult. Sci., 50:9-15
de Oliveira MC, da Silva DM, Dias DMB. 2013. Effect of feed restriction on organs and intestinal mucosa of growing rabbits. R. Bras. Zootec., 42(7):530-534
El-Gogary MR, El-Moghazy MM, El-Atrsh A, Tousson E. 2014. Effect of fish oil administration on growth performance, some blood parameters, duodenum and caecum histology of growing rabbits. Egypt. J. Basic Appl. Phsiol., 13:45-56
Elnasharty MAI, Abou-Ghanema, Sayed-Ahmed A, Elnour AA. 2013. Mucosal- submucosal changes in rabbit duodenum during development. World Academy of Science, Engineering and Technology, 76:500-508
Ermayanti NGAM, Oka IGL, Mahardika IG, Suyadnya IP. 2018. Profil lipid kelinci (Lepus sp.) jantan lokal yang diberi pakan komersial disuplementasi minyak hati ikan kod. Jurnal Biologi Udayana, 22(1):7-12
Ezema C, Eze C. 2012. Determination of The effect of probiotic (Saccharomyces cerevisiae) on growth performance and hematological parameters of rabbits. Comaparative Clinical Pathology, 21:73-76
Fenton JI, Hord NG, Ghosh S. 2013. Immunomodulation by dietary long chain omega-3 fatty acids and the potential for adverse health outcomes. Prostaglandins Leukot Essent Fatty Acids, 89:379-390
Gholami H, Chamani M, Towhidi A, Fazeli MH. 2011. Improvement of semen quality in holstein bulls during heat stress by dietary supplementation of omega-3 fatty acids. Int. J. Fertil. Steril., 4(4):160-167
Gurr MI, Harwood JL, Frayn KN, Murphy DJ, Michell RH. 2016. Lipids: Biochemistry, Biotechnology and Health, 6th ed., Wiley/Blackwell: Oxford, UK
Hidayat SCM, Harimurti S, Yusiati LM. 2016. Pengaruh suplementasi probiotik bakteri asam laktat terhadap histomorfologi usus dan performan puyuh jantan. Buletin Peternakan. 40 (2): 101-106
Ilsley SE, Miller HM, Kamel C. 2005. Effects of dietary quillaja saponin and curcumin on the performance and immune status of weaned piglets. J. Anim. Sci., 83:82-88
Kalish BT, Fallon EM, Puder M. 2012. A tutorial on fatty acid biology. JPEN J. Parenter Enteral Nutr., 36:380-388
Konieczka P, Barszcz M, Choct M, Smulikowska S. 2018. The interactive effect of dietary n-6:n-3 fatty acid ratio and vitamin E level on tissue lipid peroxidation, DNA damage in intestinal epithelial cells, and gut morphology in chickens of different ages. Poult. Sci., 97(1):149-158
Kowalska D, Bielanski P. 2007. Effect of Dietary fish oil supplement on rearing performance of young rabbits and quality of their meat. Pol. J. Food Nutr. Sci., 57(3):63-66
Lisnahan CV, Wihandoyo, Zuprizal, Harimurti S. 2019. Morfologi usus ayam kampung umur 20 minggu yang disuplementasi dl-metionin dan l-lisin HCL dalam pakan. Journal of Tropical Animal Science and Technology, 1(1):14-21
Luchtman DW, Song C. 2013. Cognitive enhancement by omega-3 fatty acids from child-hood to old age: findings from animal and clinical studies. Neuropharmacology. 64:550-565
Majid NC, Simanjuntak P, Suwarno T. 2019. Uji aktivitas anti hiperlipidemia minyak ikan gindara (Lepidocybium flavobrunneum) pada tikus putih jantan dewasa galur wistar. Jurnal Ilmu Kesehatan, 18(3):77-81
Menni C, Zierer J, Pallister T, Jackson MA, Long T, Mohney RP, Steves CJ, Spector TD, Valdes AM. 2017. Omega-3 fatty acids correlate with gut microbiome diversity and production of N-carbamylglutamate in middle aged and elderly women. Sci. Rep., 7:11079
Maertens L, Aerts JM, De Brabander DL. 2005. Effect of a diet rich in n-3 fatty acids on the performances and milk composition of does and the viability of their progeny. In Proc.: 11ème J. Rech. Cunicoles, Bolet G. (Ed.) ITAVI, publ., Paris, France, 29&30:205-208
Pilevar M, Arshami JAAD, Golian A, Basami MR. 2011. Effects of dietary n-6: n-3 ratio on immune and reproductive systems of pullet chicks. Poult. Sci, 90:1758-1766
Raatz SK, Redmon JB, Wimmergren N, Donadio JV, Bibus DM. 2009. Enhanced absorption of omega-3 fatty acids from emulsified compared with encapsulated fish oil. J. Am. Diet Assoc., 109:1076-1081
Rajput N, Muhammad N, Yan R, Zhong X, Wang T. 2013. Effect of dietary supplementation of curcumin on growth performance, intestinal morphology and nutrients utilization broiler chicks. J. Japan Poult Sci. Assoc., 50:44-52
Ristic-Medic D, Vucic V, Takic M, Karadzic I, Glibetic M. 2013. Polyunsaturated fatty acids in health and disease. J. Serb. Chem. Soc., 78(9):1269-1289
Samuelsson B. 2012. Role of basic science in the development of new medicines: examples from the eicosanoid field. J. Biol. Chem., 287:10070-10080
Sherwood L, Klandorf H, Yancey P. 2013. Animal Physiology: From Genes to Organism. 2rd ed. Publisher by Brooks Cole, Cengange Learning
Spector A, Kim H-Y. 2015. Discovery of essential fatty acids. J. Lipid Res., 56:11–21
Turner D, Shah PS, Steinhart AH. 2011. Maintenance of remis-sion in inflammatory bowel disease using omega-3 fatty acids (fish oil): a systematic review and meta-analyses. Inflamm Bowel Dis.,17:336-345
Vangaveti VN, Jansen H, Kennedy RL, Malabu UH. 2016. Hydroxyoctadecadienoic acids: oxidised derivatives of linoleic acid and their role in inflammation associated with metabolic syndrome and cancer. Eur. J. Pharmacol., 785:70-76
Wei Z, Wang W, Chen J, Yang D, Yan R, Cai Q. 2014. A prospective, randomized, controlled study of omega-3 fish oil fat emulsion-based parenteral nutrition for patients following surgical resection of gastric tumors. Nutrition Journal, 13:25-36
Yu H-N, Zhu J, Pan W-S, Shen S-R, Shan W-G, Das UN. 2014. Effects of fish oil with a high content of n-3 polyunsaturated fatty acids on mouse gut microbiota. Archives of Medical Research, 45(Issue 3):195-200
Zarate R, El Jaber-Vazdekis N, Tejera N, Perez JA, Rodriguez C. 2017. Significance of long chain polyunsaturated fatty acids in human health. Clin Transl Med., 6(1):25
Zeitz JO, Fennhoff J, Kluge H, Stangl GI, Eder K. 2015. Effects of dietary fats rich in lauric and myristic acid on performance, intestinal morphology, gut microbes, and meat quality in broilers. Poult. Sci., 94:2404-2413
Published
2021-06-28
How to Cite
ERMAYANTI, Ni Gusti Ayu Manik et al.
Histomorphometric of duodenum in male rabbits after fed commercial feed supplemented by cod liver oil.
Jurnal Biologi Udayana, [S.l.], v. 25, n. 1, p. 87-94, june 2021.
ISSN 2599-2856.
Available at: <https://ojs.unud.ac.id/index.php/bio/article/view/70478>. Date accessed: 26 apr. 2024.
doi: https://doi.org/10.24843/JBIOUNUD.2021.v25.i01.p10.
Section
Articles
