PERKEMBANGAN TERKINI DALAM DIAGNOSIS DAN PENATALAKSANAAN IRRITABEL BOWEL SYNDROME

Abstract

Irritable bowel syndrome (IBS) is a common gastrointestinal (GI) motility and sensory disorder that is
characterized by abdominal pain/discomfort, bloating and altered bowel habit. The disease accounts for huge
costs for both patients and health-care systems and worsens significantly patients’ quality of life. Diagnosis is
based on the identification of symptoms according to Manning, Rome I and Rome II criteria and the most recent
Rome III criteria and exclusion of alarm indicators. The treatment of IBS is centred on an excellent doctor–
patient relationship along with drugs targeting the predominant symptom, especially during exacerbations. This
review aim to explain new ctriteria to diagnose IBS and to conduct a systematic evidence-based review of
pharmacological therapies currently used, or in clinical development, for the treatment of IBS