Aktivitas Alanin Aminotransferase Dan Aspartat Aminotransferase Sapi Bali Terinfeksi Fasciola Gigantica
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https://doi.org/10.24843/bulvet.2018.v10.i01.p14
Abstrak
Alanin Aminotransferase (ALT) dan Aspartat Aminotransferase (AST) merupakan enzim-enzim aminotransferase yang sering digunakan sebagai parameter kerusakan hati. Tujuan penelitian ini adalah untuk mengetahui infeksi Fasciola gigantica pada sapi bali terhadap aktivitas ALT dan AST. Materi yang digunakan adalah 60 sampel darah sapi bali yang terdiri dari 30 sampel darah yang terinfeksi Fasciola gigantica dan 30 sampel darah yang tidak terinfeksi Fasciola gigantica. Sampel darah diambil pada saat pemotongan berlangsung dengan menggunakan tabung non EDTA. Data dianalisis dengan menggunakan Independent Samples T Test. Hasil penelitian menunjukkan rerata kadar ALT darah pada sapi bali yang terinfeksi Fasciola gigantica adalah 78,73 U/L tidak berpengaruh nyata terhadap peningkatan kadar ALT dibandingkan dengan sapi bali yang tidak terinfeksi Fasciola gigantica 57,23 U/L. Sedangkan, rerata kadar AST darah pada sapi bali yang terinfeksi Fasciola gigantica adalah 108,43 U/L berpengaruh sangat nyata terhadap peningkatan AST dibandingkan dengan sapi bali yang tidak terinfeksi Fasciola gigantica 78,13 U/L.
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Referensi
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Besung INK, Tono KPG, Rompis ALT, Suarjana IGK. 2016. Prevalensi Pasteurella multocida Pada Sapi Bali Di Bali. Bul. Vet. Udayana. 8(2): 145-150.
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Subronto. 2007. Ilmu Penyakit Ternak II (revisi). Yogyakarta: Gadjah Mada University Press, Cetakan ke-3.
Suratma NA, Dwinata IM, Oka IBM, Mubarok F, Alamsyah AN. 2016. Prevalence of Gastrointestinal Tract Worms in Bali Cattle at Bali Cattle Breeding Center, Sobangan, Badung. Proc. Intsem. LPVT. 2016: 153-155.
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Ardana IBK, Anthara MS, dan Dharmayudha AAGO, Putra DKH. 2016. Wudani Leaf Extract (Quisqualis indica Linn) as Traditional Medicine to Control the Incidence of Cattle Worm. Bali. Med. J. 6(3): 17-22.
Astiti LGS, Panjaitan T. 2012. Mapping Of Fascioliasis On Bali Cattle In Lombok. Int Confn Livestock. Prod. Vet. Technol. 2012: 416-421.
Bahri S. 1994. Fotosensitisasi dan penanggulangannya pada ternak ruminansia. Wartazoa. 3(2-4): 13-16.
Besung INK, Tono KPG, Rompis ALT, Suarjana IGK. 2016. Prevalensi Pasteurella multocida Pada Sapi Bali Di Bali. Bul. Vet. Udayana. 8(2): 145-150.
Chadwick BJ. 1998. Detection of Jembrana disease virus in spleen, lymph nodes, bone marrow and other tissues by in situ hybridization of paraffin-embedded sections. J. Gen. Virol. 79: 101-106.
Davoudi SM. 2013. Study of Hepatic Problems in livestock. Euro. J. Zool. Res. 2(4): 124-132.
Elazab MFA. 2015. Evaluation of serum enzyme activities and protein fractions in Brucella-infected cows. Turk. J. Vet. Anim. Sci. 39: 480-484.
Ford EJH. 1977. Serum enzymes in diagnosis. The. Vet. Ann. 17: 307-309
Fraser A, Longnecker M, Lawlor D. 2007. Prevalence of elevated alanine aminotransferase among US adolescents and associated factors: NHANES 1999–2004. Gastroenterology. 133: 1814–1820
Gowda S, Desai PB, Hull VV, Math AAK, Vernekar SN, Kulkarni SS. 2009. A review on laboratory liver function tests. Pan. Afr. Med. J. 3(17): 1-11.
Ismail E, Suhermiyati S, Roesdjianto. 2013. Penambahan tepung kunyit (Curcuma domestica Val) dan sambiloto (Adrographispaniculata Ness) dalam pakan terhadap bobot hati, pancreas dan empedu broiler. J. Ilmiah. Peternakan. 1(3): 750-758.
Kardena IM, Winaya IBMO, Adi AAAM, Berata IK, Adnyana IBW, Sukada IM, Agustina KK, Antara PATK. 2017. Patological Changes in Liver and Gall Bladder Of Bali Cattle Infected by Fasciolosis. J. Vet. Med. Anim. Sci. 1(1): 6-10.
Kim W, Flamm SL, Di Bisceglie AM, Bodenheimer HC. 2008. Serum activity of alanine aminotransferase (ALT) as an indicator of health and disease. Hepatology. 47(4): 1363-1370.
Kusumamiharja S. 1992. Parasit dan Parasitosis pada Hewan Ternak dan Hewan Piaraan di Indonesia. Bogor: Pusat Antar Universitas Bioteknologi Institut Pertanian Bogor.
Liu P, He BX, Yang XL, Hou XL, Zhao HY, Han YH, Nie P, Deng HF, Cheng L. 2012. Activities of Aspartate Aminotransferase, Alanine Aminotransferase, Gamma-Glutamyltransferase, Alkaline Phosphatase in Plasma of Postpartum Holstein Cows. J. Anim. Vet. Adv. 11(8): 1270-1274.
Liu Z, Que S, Xu J, Peng T. 2014. Alanine Aminotransferase-Old Biomarker and New Concept: A Review. Int. J. Med. Sci. 11(9): 925-935.
Mahato SN, Harrison LJS. 2005. Control of fasciolosis in stall-fed buffaloes by managing the feeding of rice straw. Trop. Anim. Health. Prod. 37: 285-291.
Mas-Coma MS, Valero MA, Bargues MD, Rolliasan D, Hay SL. 2009. Fasciola lymnaeids and human fasciolosis with a global overview on disease transmission, epidemiology evolutionary genetic, moleculer epidemiology and control. Adv Parasitol 69: 41-46.
Ronald A, Sacher, Richard A. McPherson. 2004. Alih bahasa: Brahm U. Pendit dan Dewi Wulandari, Editor: Huriawati Hartanto, Tinjauan Klinis Hasil Pemeriksaan Laboratorium, Edisi 11, EGC, Jakarta.
Sevinc M, Basoglu A, Birdane FM, Boydak M. 2001. Liver Function in Dairy Cows with Fatty Liver. Revue. Med. Vet. 152(4): 297-300.
Sripa B, Kaewkes S, Intapan PM, Maleewong W, Brindley PJ. 2010. Food-borne trematodiasis in Southeast Asian: epidemiology, pathology, clinical manifestation and control. Adv. Parasitol. 72: 305-350.
Stockham SL, Scott MA. 2002. Fundamentals of Veterinary Clinical Pathology. Ed. Ke-1, Blackwell publishing Co., Iowa state Pr. Pp: 433-486.
Stojevic Z, Piršljin J, Milinković-Tur S, Zdelar-Tuk M, Ljubić BB. 2005. Activities of ast, alt and ggt in clinically healthy dairy cows during lactation and in the dry period. Vet. Arhiv. 75: 67-73.
Subronto. 2007. Ilmu Penyakit Ternak II (revisi). Yogyakarta: Gadjah Mada University Press, Cetakan ke-3.
Suratma NA, Dwinata IM, Oka IBM, Mubarok F, Alamsyah AN. 2016. Prevalence of Gastrointestinal Tract Worms in Bali Cattle at Bali Cattle Breeding Center, Sobangan, Badung. Proc. Intsem. LPVT. 2016: 153-155.
Suwiti, N.K, Besung INK, Mahardika GN. 2017a. Factors influencing growth hormone levels of Bali cattle in Bali, Nusa Penida, and Sumbawa Islands, Indonesia. Vet. World. 10(10): 1250-1254.
Suwiti NK, Besung INK, Sriyani NLP, Sampurna P, Agustina KK. 2017b. Aplikasi Teknologi Pada Peternakan Sapi Bali Dengan Sistem Pemeliharaan Berbasis Terintegrasi Lingkungan. J. Udayana Mengabdi. 15(2): 216-222.
Diterbitkan
2018-02-20
##submission.howToCite##
DHARMAYUDHA, Anak Agung Gde Oka et al.
Aktivitas Alanin Aminotransferase Dan Aspartat Aminotransferase Sapi Bali Terinfeksi Fasciola Gigantica.
Buletin Veteriner Udayana, [S.l.], p. 87-92, feb. 2018.
ISSN 2477-2712.
Tersedia pada: <http://ojs.unud.ac.id/index.php/buletinvet/article/view/35669>. Tanggal Akses: 16 feb. 2026
doi: https://doi.org/10.24843/bulvet.2018.v10.i01.p14.
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